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A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
Yang Z, Nasrallah IM, Shou H, Wen J, Doshi J, Habes M, Erus G, Abdulkadir A, Resnick SM, Albert MS, Maruff P, Fripp J, Morris JC, Wolk DA, Davatzikos C; iSTAGING Consortium; Baltimore Longitudinal Study of Aging (BLSA); Alzheimer’s Disease Neuroimaging Initiative (ADNI). Yang Z, et al. Nat Commun. 2021 Dec 3;12(1):7065. doi: 10.1038/s41467-021-26703-z. Nat Commun. 2021. PMID: 34862382 Free PMC article.
Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: cui y. ArXiv [Preprint]. 2023 Jan 25:arXiv:2301.10772v1. ArXiv. 2023. PMID: 36748000 Free PMC article. Updated. Preprint.
Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease.
Sha J, Bao J, Liu K, Yang S, Wen Z, Cui Y, Wen J, Davatzikos C, Moore JH, Saykin AJ, Long Q, Shen L; ADNI. Sha J, et al. Among authors: cui y. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2022 Dec;2022:541-548. doi: 10.1109/bibm55620.2022.9995342. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2022. PMID: 36845995 Free PMC article.
Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes.
Habes M, Jacobson AM, Braffett BH, Rashid T, Ryan CM, Shou H, Cui Y, Davatzikos C, Luchsinger JA, Biessels GJ, Bebu I, Gubitosi-Klug RA, Bryan RN, Nasrallah IM; DCCT/EDIC Research Group. Habes M, et al. Among authors: cui y. JAMA Netw Open. 2023 Jun 1;6(6):e2316182. doi: 10.1001/jamanetworkopen.2023.16182. JAMA Netw Open. 2023. PMID: 37261829 Free PMC article. Clinical Trial.
The Genetic Architecture of Multimodal Human Brain Age.
Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C. Wen J, et al. Among authors: cui y. bioRxiv [Preprint]. 2023 Sep 30:2023.04.13.536818. doi: 10.1101/2023.04.13.536818. bioRxiv. 2023. PMID: 37333190 Free PMC article. Updated. Preprint.
Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability.
Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah I, Satterthwaite T, Shou H, Shen L, Toga AW, Zaleskey A, Davatzikos C. Wen J, et al. Among authors: cui y. medRxiv [Preprint]. 2023 Aug 24:2023.08.16.23294179. doi: 10.1101/2023.08.16.23294179. medRxiv. 2023. PMID: 37662256 Free PMC article. Preprint.
Genomic loci influence patterns of structural covariance in the human brain.
Wen J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, Yang Z, Erus G, Robert-Fitzgerald T, Singh A, Sotiras A, Boquet-Pujadas A, Mamourian E, Doshi J, Cui Y, Srinivasan D, Skampardoni I, Chen J, Hwang G, Bergman M, Bao J, Veturi Y, Zhou Z, Yang S, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Gur RC, Gur RE, Koutsouleris N, Wolf DH, Saykin AJ, Ritchie MD, Shen L, Thompson PM, Colliot O, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Fan Y, Habes M, Wolk D, Shou H, Davatzikos C. Wen J, et al. Among authors: cui y. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2300842120. doi: 10.1073/pnas.2300842120. Epub 2023 Dec 21. Proc Natl Acad Sci U S A. 2023. PMID: 38127979
Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: cui y. Nat Commun. 2024 Jan 8;15(1):354. doi: 10.1038/s41467-023-44271-2. Nat Commun. 2024. PMID: 38191573 Free PMC article.
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