Characterization of articular cartilage homeostasis and the mechanism of superior cartilage regeneration of MRL/MpJ mice.
Deng Z, Gao X, Sun X, Amra S, Lu A, Cui Y, Eltzschig HK, Lei G, Huard J.
Deng Z, et al. Among authors: cui y.
FASEB J. 2019 Aug;33(8):8809-8821. doi: 10.1096/fj.201802132RR. Epub 2019 May 1.
FASEB J. 2019.
PMID: 31042406
Collectively, our study revealed that down-regulation of pSMAD2/3, beta-catenin, and MMPs and up-regulation of pSMAD5 and M2a macrophage polarization contribute to the enhanced cartilage repair observed in MRL/MpJ mice.-Deng, Z., Gao, X., Sun, X., Amra, S., Lu, A., Cui, …
Collectively, our study revealed that down-regulation of pSMAD2/3, beta-catenin, and MMPs and up-regulation of pSMAD5 and M2a macrophage pol …