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A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
IRF4 International Consortium; Fornes O, Jia A, Kuehn HS, Min Q, Pannicke U, Schleussner N, Thouenon R, Yu Z, de Los Angeles Astbury M, Biggs CM, Galicchio M, Garcia-Campos JA, Gismondi S, Gonzalez Villarreal G, Hildebrand KJ, Hönig M, Hou J, Moshous D, Pittaluga S, Qian X, Rozmus J, Schulz AS, Staines-Boone AT, Sun B, Sun J, Uwe S, Venegas-Montoya E, Wang W, Wang X, Ying W, Zhai X, Zhou Q, Akalin A, André I, Barth TFE, Baumann B, Brüstle A, Burgio G, Bustamante JC, Casanova JL, Casarotto MG, Cavazzana M, Chentout L, Cockburn IA, Costanza M, Cui C, Daumke O, Del Bel KL, Eibel H, Feng X, Franke V, Gebhardt JCM, Götz A, Grunwald S, Hoareau B, Hughes TR, Jacobsen EM, Janz M, Jolma A, Lagresle-Peyrou C, Lai N, Li Y, Lin S, Lu HY, Lugo-Reyes SO, Meng X, Möller P, Moreno-Corona N, Niemela JE, Novakovsky G, Perez-Caraballo JJ, Picard C, Poggi L, Puig-Lombardi ME, Randall KL, Reisser A, Schmitt Y, Seneviratne S, Sharma M, Stoddard J, Sundararaj S, Sutton H, Tran LQ, Wang Y, Wasserman WW, Wen Z, Winkler W, Xiong E, Yang AWH, Yu M, Zhang L, Zhang H, Zhao Q, Zhen X, Enders A, Kracker S, Martinez-Barricarte R, Mathas S, Rosenzweig SD, Schwarz K, Turvey SE, Wang JY. IRF4 International Consortium, et al. Among authors: cui c. Sci Immunol. 2023 Jan 20;8(79):eade7953. doi: 10.1126/sciimmunol.ade7953. Epub 2023 Jan 20. Sci Immunol. 2023. PMID: 36662884 Free PMC article.
Effective and safe treatment of a novel IL2RA deficiency with rapamycin.
Lai N, Liu L, Lin L, Cui C, Wang Y, Min Q, Xiong E, Wang W, Ying W, Zhou Q, Hou J, Sun J, Wang JY, Wang X. Lai N, et al. Among authors: cui c. J Allergy Clin Immunol Pract. 2020 Mar;8(3):1132-1135.e4. doi: 10.1016/j.jaip.2019.09.027. Epub 2019 Oct 9. J Allergy Clin Immunol Pract. 2020. PMID: 31605764 No abstract available.
MZB1 promotes the secretion of J-chain-containing dimeric IgA and is critical for the suppression of gut inflammation.
Xiong E, Li Y, Min Q, Cui C, Liu J, Hong R, Lai N, Wang Y, Sun J, Matsumoto R, Takahashi D, Hase K, Shinkura R, Tsubata T, Wang JY. Xiong E, et al. Among authors: cui c. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13480-13489. doi: 10.1073/pnas.1904204116. Epub 2019 May 24. Proc Natl Acad Sci U S A. 2019. PMID: 31127044 Free PMC article.
LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway.
Wang Y, Liu J, Akatsu C, Zhang R, Zhang H, Zhu H, Liu K, Zhu HY, Min Q, Meng X, Cui C, Tang Y, Yu M, Li Y, Feng X, Wei H, Wen Z, Ji S, Weigert MG, Tsubata T, Wang JY. Wang Y, et al. Among authors: cui c. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2205629119. doi: 10.1073/pnas.2205629119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037365 Free PMC article.
Structural basis of human NOX5 activation.
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J. Cui C, et al. Nat Commun. 2024 May 11;15(1):3994. doi: 10.1038/s41467-024-48467-y. Nat Commun. 2024. PMID: 38734761 Free PMC article.
3,923 results