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Page 1
Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial.
Major Extremity Trauma Research Consortium (METRC); O'Toole RV, Joshi M, Carlini AR, Murray CK, Allen LE, Huang Y, Scharfstein DO, O'Hara NN, Gary JL, Bosse MJ, Castillo RC, Bishop JA, Weaver MJ, Firoozabadi R, Hsu JR, Karunakar MA, Seymour RB, Sims SH, Churchill C, Brennan ML, Gonzales G, Reilly RM, Zura RD, Howes CR, Mir HR, Wagstrom EA, Westberg J, Gaski GE, Kempton LB, Natoli RM, Sorkin AT, Virkus WW, Hill LC, Hymes RA, Holzman M, Malekzadeh AS, Schulman JE, Ramsey L, Cuff JAN, Haaser S, Osgood GM, Shafiq B, Laljani V, Lee OC, Krause PC, Rowe CJ, Hilliard CL, Morandi MM, Mullins A, Achor TS, Choo AM, Munz JW, Boutte SJ, Vallier HA, Breslin MA, Frisch HM, Kaufman AM, Large TM, LeCroy CM, Riggsbee C, Smith CS, Crickard CV, Phieffer LS, Sheridan E, Jones CB, Sietsema DL, Reid JS, Ringenbach K, Hayda R, Evans AR, Crisco MJ, Rivera JC, Osborn PM, Kimmel J, Stawicki SP, Nwachuku CO, Wojda TR, Rehman S, Donnelly JM, Caroom C, Jenkins MD, Boulton CL, Costales TG, LeBrun CT, Manson TT, Mascarenhas DC, Nascone JW, Pollak AN, Sciadini MF, Slobogean GP, Berger PZ, Connelly DW, Degani Y, Howe AL, Marinos DP, Montalvo RN, Reahl GB, Schoonover CD, Schroder LK, Vang S, Bergin PF, Grave… See abstract for full author list ➔ Major Extremity Trauma Research Consortium (METRC), et al. Among authors: cuff jan. JAMA Surg. 2021 May 1;156(5):e207259. doi: 10.1001/jamasurg.2020.7259. Epub 2021 May 12. JAMA Surg. 2021. PMID: 33760010 Clinical Trial.
Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair: The PREP-IT Master Protocol.
Program of Randomized Trials to Evaluate Pre-operative Antiseptic Skin Solutions in Orthopaedic Trauma (PREP-IT) Investigators; Slobogean GP, Sprague S, Wells J, Bhandari M, Rojas A, Garibaldi A, Wood A, Howe A, Harris AD, Petrisor BA, Mullins DC, Pogorzelski D, Marvel D, Heels-Ansdell D, Mossuto F, Grissom F, Del Fabbro G, Guyatt GH, Della Rocca GJ, Demyanovich HK, Gitajn IL, Palmer J, D'Alleyrand JC, Friedrich J, Rivera J, Hebden J, Rudnicki J, Fowler J, Jeray KJ, Thabane L, Marchand L, O'Hara LM, Joshi MG, Talbot M, Camara M, Szasz OP, O'Hara NN, McKay P, Devereaux PJ, O'Toole RV, Zura R, Morshed S, Dodds S, Li S, Tanner SL, Scott T, Nguyen U. Program of Randomized Trials to Evaluate Pre-operative Antiseptic Skin Solutions in Orthopaedic Trauma (PREP-IT) Investigators, et al. JAMA Netw Open. 2020 Apr 1;3(4):e202215. doi: 10.1001/jamanetworkopen.2020.2215. JAMA Netw Open. 2020. PMID: 32259266 Free PMC article. Clinical Trial.
What's Important: Patient Engagement in Research.
Hale D, Marvel D, Wells J; PREP-IT Investigators. Hale D, et al. J Bone Joint Surg Am. 2020 Oct 21;102(20):1836-1838. doi: 10.2106/JBJS.19.00625. J Bone Joint Surg Am. 2020. PMID: 33086354 No abstract available.
Engaging patients as partners in a multicentre trial of spinal versus general anaesthesia for older adults.
Hruslinski J, Menio DA, Hymes RA, Jaffe JD, Langlois C, Ramsey L, Gaskins LJ, Neuman MD; Regional Versus General Anesthesia for Promoting Independence After Hip Fracture Investigators. Hruslinski J, et al. Br J Anaesth. 2021 Feb;126(2):395-403. doi: 10.1016/j.bja.2020.09.052. Epub 2020 Dec 3. Br J Anaesth. 2021. PMID: 33279102 Free article. Clinical Trial.
Low Adherence to Recommended Guidelines for Open Fracture Antibiotic Prophylaxis.
Lin CA, O'Hara NN, Sprague S, O'Toole RV, Joshi M, Harris AD, Warner SJ, Johal H, Natoli RM, Hagen JE, Jeray KJ, Fowler JT, Phelps KD, Pilson HT, Gitajn IL, Bhandari M, Slobogean GP; the PREP-IT Investigators. Lin CA, et al. J Bone Joint Surg Am. 2021 Apr 7;103(7):609-617. doi: 10.2106/JBJS.20.01229. J Bone Joint Surg Am. 2021. PMID: 33411466
Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial.
Pogorzelski D, Nguyen U, McKay P, Thabane L, Camara M, Ramsey L, Seymour R, Goodman JB, McGee S, Fraifogl J, Hudgins A, Tanner SL, Bhandari M, Slobogean GP, Sprague S; PREP-IT Investigators Executive Committee:; Steering Committee; Adjudication Committee; Data and Safety Monitoring Committee; Research Methodology Core; Patient Centred Outcomes Core; Orthopaedic Surgery Core; Operating Room Core; Infectious Disease Core; Military Core; McMaster University Methods Center; University of Maryland School of Medicine Administrative Center; University of Maryland School of Pharmacy, The PATIENTS Program; PREP-IT Clinical Sites: Lead Clinical Site (Aqueous-PREP and PREPARE); Aqueous-PREP and PREPARE; Aqueous-PREP; PREPARE; PREP-IT Investigators Executive Committee. Pogorzelski D, et al. Contemp Clin Trials Commun. 2021 Jan 23;21:100730. doi: 10.1016/j.conctc.2021.100730. eCollection 2021 Mar. Contemp Clin Trials Commun. 2021. PMID: 33605946 Free PMC article.
Pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solution in open fractures (Aqueous-PREP): the feasibility of a cluster randomized crossover study.
Sprague S, Guyatt P, Bzovsky S, Nguyen U, Bhandari M, Thabane L, Petrisor B, Johal HS, Leonard J, Dodds S, Mossuto F, O'Toole RV, Howe A, Demyanovich HK, Camara M, O'Hara NN, Slobogean GP; PREP-IT Investigators. Sprague S, et al. Pilot Feasibility Stud. 2021 Mar 1;7(1):61. doi: 10.1186/s40814-021-00800-8. Pilot Feasibility Stud. 2021. PMID: 33648577 Free PMC article.
Patient and stakeholder engagement learnings: PREP-IT as a case study.
Medeiros M, Love TR, Slobogean GP, Sprague S, Perfetto EM, O'Hara NN, Mullins CD; PREP-IT Investigators:. Medeiros M, et al. J Comp Eff Res. 2021 Apr;10(6):439-442. doi: 10.2217/cer-2020-0266. Epub 2021 Mar 24. J Comp Eff Res. 2021. PMID: 33759556 Free article. No abstract available.
Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials.
Pechero G Jr, Pfaff B, Rao M, Pogorzelski D, McKay P, Spicer E, Howe A, Demyanovich HK, Sietsema DL, McTague MF, Ramsey L, Holden M, Rudnicki J, Wells J, Medeiros M, Slobogean GP, Sprague S; PREP-IT Investigators; Slobogean GP, Sprague S, Wells J, Bhandari M; Steering Committee; Adjudication Committee; Data and Safety Monitoring Committee; Research Methodology Core; Patient Centred Outcomes Core; Orthopaedic Surgery Core; Operating Room Core; Infectious Disease Core; Military Core; PREP-IT Clinical Sites; O'Toole RV, D'Alleyrand JC, Eglseder A, Johnson A, Langhammer C, Lebrun C, Manson T, Nascone J, Paryavi E, Pensy R, Pollak A, Sciadini M, Slobogean GP, Degani Y, Demyanovich HK, Howe A, O'Hara NN, Joseph K, Rudnicki J, Camara M; Aqueous-PREP and PREPARE; Aqueous-PREP; PREPARE. Pechero G Jr, et al. Contemp Clin Trials Commun. 2021 Jun 14;22:100787. doi: 10.1016/j.conctc.2021.100787. eCollection 2021 Jun. Contemp Clin Trials Commun. 2021. PMID: 34195467 Free PMC article.
Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults.
Neuman MD, Feng R, Carson JL, Gaskins LJ, Dillane D, Sessler DI, Sieber F, Magaziner J, Marcantonio ER, Mehta S, Menio D, Ayad S, Stone T, Papp S, Schwenk ES, Elkassabany N, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes RA, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Giska M, Ranganath Y, Tedore T, Choi S, Li J, Kwofie MK, Nader A, Sanders RD, Allen BFS, Vlassakov K, Kates S, Fleisher LA, Dattilo J, Tierney A, Stephens-Shields AJ, Ellenberg SS; REGAIN Investigators. Neuman MD, et al. N Engl J Med. 2021 Nov 25;385(22):2025-2035. doi: 10.1056/NEJMoa2113514. Epub 2021 Oct 9. N Engl J Med. 2021. PMID: 34623788 Clinical Trial.
18 results