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JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma.
Manieri E, Folgueira C, Rodríguez ME, Leiva-Vega L, Esteban-Lafuente L, Chen C, Cubero FJ, Barrett T, Cavanagh-Kyros J, Seruggia D, Rosell A, Sanchez-Cabo F, Gómez MJ, Monte MJ, G Marin JJ, Davis RJ, Mora A, Sabio G. Manieri E, et al. Among authors: cubero fj. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16492-16499. doi: 10.1073/pnas.2002672117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601222 Free PMC article.
Bone marrow-derived c-jun N-terminal kinase-1 (JNK1) mediates liver regeneration.
Schaefer FM, Peng J, Hu W, Drvarov O, Nevzorova YA, Zhao G, Masaoudi MA, Davis RJ, Trautwein C, Cubero FJ. Schaefer FM, et al. Among authors: cubero fj. Biochim Biophys Acta. 2015 Jan;1852(1):137-45. doi: 10.1016/j.bbadis.2014.10.011. Epub 2014 Oct 22. Biochim Biophys Acta. 2015. PMID: 25445542 Free article.
Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.
Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M, Preisinger C, Gassler N, Canbay AE, Luedde T, Davis RJ, Liedtke C, Trautwein C. Cubero FJ, et al. Gastroenterology. 2016 Apr;150(4):968-81. doi: 10.1053/j.gastro.2015.12.019. Epub 2015 Dec 19. Gastroenterology. 2016. PMID: 26708719 Free PMC article.
Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma.
Sonntag R, Giebeler N, Nevzorova YA, Bangen JM, Fahrenkamp D, Lambertz D, Haas U, Hu W, Gassler N, Cubero FJ, Müller-Newen G, Abdallah AT, Weiskirchen R, Ticconi F, Costa IG, Barbacid M, Trautwein C, Liedtke C. Sonntag R, et al. Among authors: cubero fj. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9282-9287. doi: 10.1073/pnas.1807155115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150405 Free PMC article.
Adiponectin accounts for gender differences in hepatocellular carcinoma incidence.
Manieri E, Herrera-Melle L, Mora A, Tomás-Loba A, Leiva-Vega L, Fernández DI, Rodríguez E, Morán L, Hernández-Cosido L, Torres JL, Seoane LM, Cubero FJ, Marcos M, Sabio G. Manieri E, et al. Among authors: cubero fj. J Exp Med. 2019 May 6;216(5):1108-1119. doi: 10.1084/jem.20181288. Epub 2019 Apr 3. J Exp Med. 2019. PMID: 30944152 Free PMC article.
p38γ is essential for cell cycle progression and liver tumorigenesis.
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Tomás-Loba A, et al. Among authors: cubero fj. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. Nature. 2019. PMID: 30971822
Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach.
Urman JM, Herranz JM, Uriarte I, Rullán M, Oyón D, González B, Fernandez-Urién I, Carrascosa J, Bolado F, Zabalza L, Arechederra M, Alvarez-Sola G, Colyn L, Latasa MU, Puchades-Carrasco L, Pineda-Lucena A, Iraburu MJ, Iruarrizaga-Lejarreta M, Alonso C, Sangro B, Purroy A, Gil I, Carmona L, Cubero FJ, Martínez-Chantar ML, Banales JM, Romero MR, Macias RIR, Monte MJ, Marín JJG, Vila JJ, Corrales FJ, Berasain C, Fernández-Barrena MG, Avila MA. Urman JM, et al. Among authors: cubero fj. Cancers (Basel). 2020 Jun 21;12(6):1644. doi: 10.3390/cancers12061644. Cancers (Basel). 2020. PMID: 32575903 Free PMC article.
117 results