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Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.
Li L, Chenna BC, Yang KS, Cole TR, Goodall ZT, Giardini M, Moghadamchargari Z, Hernandez EA, Gomez J, Calvet CM, Bernatchez JA, Mellott DM, Zhu J, Rademacher A, Thomas D, Blankenship LR, Drelich A, Laganowsky A, Tseng CK, Liu WR, Wand AJ, Cruz-Reyes J, Siqueira-Neto JL, Meek TD. Li L, et al. Among authors: cruz reyes j. J Med Chem. 2021 Aug 12;64(15):11267-11287. doi: 10.1021/acs.jmedchem.1c00628. Epub 2021 Jul 21. J Med Chem. 2021. PMID: 34288674 Free PMC article.
Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity.
Chenna BC, Li L, Mellott DM, Zhai X, Siqueira-Neto JL, Calvet Alvarez C, Bernatchez JA, Desormeaux E, Alvarez Hernandez E, Gomez J, McKerrow JH, Cruz-Reyes J, Meek TD. Chenna BC, et al. Among authors: cruz reyes j. J Med Chem. 2020 Mar 26;63(6):3298-3316. doi: 10.1021/acs.jmedchem.9b02078. Epub 2020 Mar 17. J Med Chem. 2020. PMID: 32125159 Free PMC article.
Trypanosome RNA helicase KREH2 differentially controls non-canonical editing and putative repressive structure via a novel proposed 'bifunctional' gRNA in mRNA A6.
Meehan J, McDermott SM, Ivens A, Goodall Z, Chen Z, Yu Z, Woo J, Rodshagen T, McCleskey L, Sechrist R, Stuart K, Zeng L, Rouskin S, Savill NJ, Schnaufer A, Zhang X, Cruz-Reyes J. Meehan J, et al. Among authors: cruz reyes j. Nucleic Acids Res. 2023 Jul 21;51(13):6944-6965. doi: 10.1093/nar/gkad453. Nucleic Acids Res. 2023. PMID: 37246647 Free PMC article.
49 results