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Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.
da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y, Zhang Y, Foox J, Zanello S, Crucian B, Wang D, Nugent A, Costa HA, Zwart SR, Schrepfer S, Elworth RAL, Sapoval N, Treangen T, MacKay M, Gokhale NS, Horner SM, Singh LN, Wallace DC, Willey JS, Schisler JC, Meller R, McDonald JT, Fisch KM, Hardiman G, Taylor D, Mason CE, Costes SV, Beheshti A. da Silveira WA, et al. Among authors: crucian b. Cell. 2020 Nov 25;183(5):1185-1201.e20. doi: 10.1016/j.cell.2020.11.002. Cell. 2020. PMID: 33242417 Free PMC article.
Increased core body temperature in astronauts during long-duration space missions.
Stahn AC, Werner A, Opatz O, Maggioni MA, Steinach M, von Ahlefeld VW, Moore A, Crucian BE, Smith SM, Zwart SR, Schlabs T, Mendt S, Trippel T, Koralewski E, Koch J, Choukèr A, Reitz G, Shang P, Röcker L, Kirsch KA, Gunga HC. Stahn AC, et al. Sci Rep. 2017 Nov 23;7(1):16180. doi: 10.1038/s41598-017-15560-w. Sci Rep. 2017. PMID: 29170507 Free PMC article.
Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.
Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, Zwart SR, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Lorenzi H, Buchheim JI, Makedonas G, Ginsburg GS, Ott CM, Pierson DL, Krieger SS, Baecker N, Sams C. Crucian BE, et al. Front Immunol. 2018 Jun 28;9:1437. doi: 10.3389/fimmu.2018.01437. eCollection 2018. Front Immunol. 2018. PMID: 30018614 Free PMC article. Review.
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW. Garrett-Bakelman FE, et al. Among authors: crucian be. Science. 2019 Apr 12;364(6436):eaau8650. doi: 10.1126/science.aau8650. Science. 2019. PMID: 30975860 Free PMC article.
Specific Immunologic Countermeasure Protocol for Deep-Space Exploration Missions.
Makedonas G, Mehta S, Choukèr A, Simpson RJ, Marshall G, Orange JS, Aunon-Chancellor S, Smith SM, Zwart SR, Stowe RP, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Krieger SS, Lorenzi H, Buchheim JI, Ginsburg GS, Ott CM, Downs M, Pierson D, Baecker N, Sams C, Crucian B. Makedonas G, et al. Among authors: crucian b. Front Immunol. 2019 Oct 11;10:2407. doi: 10.3389/fimmu.2019.02407. eCollection 2019. Front Immunol. 2019. PMID: 31681296 Free PMC article. No abstract available.
Countermeasures-based Improvements in Stress, Immune System Dysregulation and Latent Herpesvirus Reactivation onboard the International Space Station - Relevance for Deep Space Missions and Terrestrial Medicine.
Crucian BE, Makedonas G, Sams CF, Pierson DL, Simpson R, Stowe RP, Smith SM, Zwart SR, Krieger SS, Rooney B, Douglas G, Downs M, Nelman-Gonzalez M, Williams TJ, Mehta S. Crucian BE, et al. Neurosci Biobehav Rev. 2020 Aug;115:68-76. doi: 10.1016/j.neubiorev.2020.05.007. Epub 2020 May 25. Neurosci Biobehav Rev. 2020. PMID: 32464118 Free article. Review.
Arterial structure and function during and after long-duration spaceflight.
Lee SMC, Ribeiro LC, Martin DS, Zwart SR, Feiveson AH, Laurie SS, Macias BR, Crucian BE, Krieger S, Weber D, Grune T, Platts SH, Smith SM, Stenger MB. Lee SMC, et al. Among authors: crucian be. J Appl Physiol (1985). 2020 Jul 1;129(1):108-123. doi: 10.1152/japplphysiol.00550.2019. Epub 2020 Jun 11. J Appl Physiol (1985). 2020. PMID: 32525433 Free article.
Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight.
Luxton JJ, McKenna MJ, Lewis A, Taylor LE, George KA, Dixit SM, Moniz M, Benegas W, Mackay MJ, Mozsary C, Butler D, Bezdan D, Meydan C, Crucian BE, Zwart SR, Smith SM, Mason CE, Bailey SM. Luxton JJ, et al. Cell Rep. 2020 Dec 8;33(10):108457. doi: 10.1016/j.celrep.2020.108457. Epub 2020 Nov 25. Cell Rep. 2020. PMID: 33242406 Free article.
101 results