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LINE1 are spliced in non-canonical transcript variants to regulate T cell quiescence and exhaustion.
Marasca F, Sinha S, Vadalà R, Polimeni B, Ranzani V, Paraboschi EM, Burattin FV, Ghilotti M, Crosti M, Negri ML, Campagnoli S, Notarbartolo S, Sartore-Bianchi A, Siena S, Prati D, Montini G, Viale G, Torre O, Harari S, Grifantini R, Soldà G, Biffo S, Abrignani S, Bodega B. Marasca F, et al. Among authors: crosti m. Nat Genet. 2022 Feb;54(2):180-193. doi: 10.1038/s41588-021-00989-7. Epub 2022 Jan 17. Nat Genet. 2022. PMID: 35039641
Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation.
de Candia P, Torri A, Gorletta T, Fedeli M, Bulgheroni E, Cheroni C, Marabita F, Crosti M, Moro M, Pariani E, Romanò L, Esposito S, Mosca F, Rossetti G, Rossi RL, Geginat J, Casorati G, Dellabona P, Pagani M, Abrignani S. de Candia P, et al. Among authors: crosti m. PLoS One. 2013 Sep 26;8(9):e75348. doi: 10.1371/journal.pone.0075348. eCollection 2013. PLoS One. 2013. PMID: 24205408 Free PMC article.
IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells.
Kastirr I, Maglie S, Paroni M, Alfen JS, Nizzoli G, Sugliano E, Crosti MC, Moro M, Steckel B, Steinfelder S, Stölzel K, Romagnani C, Botti F, Caprioli F, Pagani M, Abrignani S, Geginat J. Kastirr I, et al. Among authors: crosti mc. J Immunol. 2014 Oct 1;193(7):3322-31. doi: 10.4049/jimmunol.1400775. Epub 2014 Aug 29. J Immunol. 2014. PMID: 25172491 Clinical Trial.
Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
De Simone M, Arrigoni A, Rossetti G, Gruarin P, Ranzani V, Politano C, Bonnal RJP, Provasi E, Sarnicola ML, Panzeri I, Moro M, Crosti M, Mazzara S, Vaira V, Bosari S, Palleschi A, Santambrogio L, Bovo G, Zucchini N, Totis M, Gianotti L, Cesana G, Perego RA, Maroni N, Pisani Ceretti A, Opocher E, De Francesco R, Geginat J, Stunnenberg HG, Abrignani S, Pagani M. De Simone M, et al. Among authors: crosti m. Immunity. 2016 Nov 15;45(5):1135-1147. doi: 10.1016/j.immuni.2016.10.021. Immunity. 2016. PMID: 27851914 Free PMC article.
Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity.
Torri A, Carpi D, Bulgheroni E, Crosti MC, Moro M, Gruarin P, Rossi RL, Rossetti G, Di Vizio D, Hoxha M, Bollati V, Gagliani C, Tacchetti C, Paroni M, Geginat J, Corti L, Venegoni L, Berti E, Pagani M, Matarese G, Abrignani S, de Candia P. Torri A, et al. Among authors: crosti mc. J Biol Chem. 2017 Feb 17;292(7):2903-2915. doi: 10.1074/jbc.M116.769893. Epub 2017 Jan 11. J Biol Chem. 2017. PMID: 28077577 Free PMC article.
Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.
Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J. Alfen JS, et al. Among authors: crosti mc. J Allergy Clin Immunol. 2018 Nov;142(5):1537-1547.e8. doi: 10.1016/j.jaci.2017.12.984. Epub 2018 Jan 31. J Allergy Clin Immunol. 2018. PMID: 29369775 Free article.
52 results