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A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells.
Pan X, Heacock ML, Abdulaziz EN, Violante S, Zuckerman AL, Shrestha N, Yao C, Goodman RP, Cross JR, Cracan V. Pan X, et al. Among authors: cross jr. Nat Chem Biol. 2024 May;20(5):594-604. doi: 10.1038/s41589-023-01460-w. Epub 2023 Oct 26. Nat Chem Biol. 2024. PMID: 37884806 Free PMC article.
Stable Isotope Tracers for Metabolic Pathway Analysis.
Violante S, Berisa M, Thomas TH, Cross JR. Violante S, et al. Among authors: cross jr. Methods Mol Biol. 2019;1978:269-283. doi: 10.1007/978-1-4939-9236-2_17. Methods Mol Biol. 2019. PMID: 31119669
Vitamin B6 Addiction in Acute Myeloid Leukemia.
Chen CC, Li B, Millman SE, Chen C, Li X, Morris JP 4th, Mayle A, Ho YJ, Loizou E, Liu H, Qin W, Shah H, Violante S, Cross JR, Lowe SW, Zhang L. Chen CC, et al. Among authors: cross jr. Cancer Cell. 2020 Jan 13;37(1):71-84.e7. doi: 10.1016/j.ccell.2019.12.002. Cancer Cell. 2020. PMID: 31935373 Free PMC article.
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells.
Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Campbell C, et al. Among authors: cross jr. Nature. 2020 May;581(7809):475-479. doi: 10.1038/s41586-020-2193-0. Epub 2020 Apr 15. Nature. 2020. PMID: 32461639 Free PMC article.
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome.
Rao SD, Chen Q, Wang Q, Orth-He EL, Saoi M, Griswold AR, Bhattacharjee A, Ball DP, Huang HC, Chui AJ, Covelli DJ, You S, Cross JR, Bachovchin DA. Rao SD, et al. Among authors: cross jr. Nat Chem Biol. 2022 May;18(5):565-574. doi: 10.1038/s41589-021-00964-7. Epub 2022 Feb 14. Nat Chem Biol. 2022. PMID: 35165443 Free PMC article.
MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT.
Andrlová H, Miltiadous O, Kousa AI, Dai A, DeWolf S, Violante S, Park HY, Janaki-Raman S, Gardner R, El Daker S, Slingerland J, Giardina P, Clurman A, Gomes ALC, Nguyen C, da Silva MB, Armijo GK, Lee N, Zappasodi R, Chaligne R, Masilionis I, Fontana E, Ponce D, Cho C, Bush A, Hill L, Chao N, Sung AD, Giralt S, Vidal EH, Hosszu KK, Devlin SM, Peled JU, Cross JR, Perales MA, Godfrey DI, van den Brink MRM, Markey KA. Andrlová H, et al. Among authors: cross jr. Sci Transl Med. 2022 May 25;14(646):eabj2829. doi: 10.1126/scitranslmed.abj2829. Epub 2022 May 25. Sci Transl Med. 2022. PMID: 35613281 Free PMC article.
207 results