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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance.
Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S, Georgouli M, Bridgeman V, Karagiannis P, Lee R, Pandya P, Boehme L, Wallberg F, Tape C, Karagiannis SN, Malanchi I, Sanz-Moreno V. Orgaz JL, et al. Among authors: crosas molist e. Cancer Cell. 2020 Jan 13;37(1):85-103.e9. doi: 10.1016/j.ccell.2019.12.003. Cancer Cell. 2020. PMID: 31935375 Free PMC article.
TGFΒ-induced transcription in cancer.
Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V. Cantelli G, et al. Semin Cancer Biol. 2017 Feb;42:60-69. doi: 10.1016/j.semcancer.2016.08.009. Epub 2016 Aug 30. Semin Cancer Biol. 2017. PMID: 27586372 Free PMC article. Review.
Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.
Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I, Ilieva KM, Cantelli G, Karagiannis P, Mele S, Lam H, Josephs DH, Matias-Guiu X, Marti RM, Nestle FO, Orgaz JL, Malanchi I, Fruhwirth GO, Karagiannis SN, Sanz-Moreno V. Georgouli M, et al. Cell. 2019 Feb 7;176(4):757-774.e23. doi: 10.1016/j.cell.2018.12.038. Epub 2019 Jan 31. Cell. 2019. PMID: 30712866 Free PMC article.
Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition.
López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E, Sanz-Moreno V, Fabregat I. López-Luque J, et al. Among authors: crosas molist e. Cancer Lett. 2019 Nov 1;464:15-24. doi: 10.1016/j.canlet.2019.08.011. Epub 2019 Aug 26. Cancer Lett. 2019. PMID: 31465839 Free PMC article.
PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control.
Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigué A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardón C, Fernández-Ruiz S, Rodriguez-Hernandez I, Hermanova I, Astobiza I, Cortazar AR, Corres-Mendizabal J, Gomez-Muñoz A, Sanz-Moreno V, Torrano V, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: crosas molist e. Cancer Res. 2019 Dec 15;79(24):6153-6165. doi: 10.1158/0008-5472.CAN-19-1231. Epub 2019 Oct 8. Cancer Res. 2019. PMID: 31594836
A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
Maiques O, Fanshawe B, Crosas-Molist E, Rodriguez-Hernandez I, Volpe A, Cantelli G, Boehme L, Orgaz JL, Mardakheh FK, Sanz-Moreno V, Fruhwirth GO. Maiques O, et al. Among authors: crosas molist e. Br J Cancer. 2021 Aug;125(5):699-713. doi: 10.1038/s41416-021-01442-6. Epub 2021 Jun 25. Br J Cancer. 2021. PMID: 34172930 Free PMC article.
Podoplanin drives dedifferentiation and amoeboid invasion of melanoma.
de Winde CM, George SL, Crosas-Molist E, Hari-Gupta Y, Arp AB, Benjamin AC, Millward LJ, Makris S, Carver A, Imperatore V, Martínez VG, Sanz-Moreno V, Acton SE. de Winde CM, et al. Among authors: crosas molist e. iScience. 2021 Aug 13;24(9):102976. doi: 10.1016/j.isci.2021.102976. eCollection 2021 Sep 24. iScience. 2021. PMID: 34485858 Free PMC article.
Rho GTPase signaling in cancer progression and dissemination.
Crosas-Molist E, Samain R, Kohlhammer L, Orgaz JL, George SL, Maiques O, Barcelo J, Sanz-Moreno V. Crosas-Molist E, et al. Physiol Rev. 2022 Jan 1;102(1):455-510. doi: 10.1152/physrev.00045.2020. Epub 2021 Sep 20. Physiol Rev. 2022. PMID: 34541899 Free article. Review.
23 results