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Page 1
Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.
Yang C, Shen HC, Wu Z, Chu HD, Cox JM, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Bateman T, Xu L, Tong X, Crook M, Sinclair P. Yang C, et al. Among authors: crook m. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4388-92. doi: 10.1016/j.bmcl.2013.05.077. Epub 2013 Jun 4. Bioorg Med Chem Lett. 2013. PMID: 23777778
Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.
Cox JM, Chu HD, Yang C, Shen HC, Wu Z, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Bateman T, Xu L, Tong X, Crook M, Sinclair P. Cox JM, et al. Among authors: crook m. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1681-4. doi: 10.1016/j.bmcl.2014.02.057. Epub 2014 Mar 1. Bioorg Med Chem Lett. 2014. PMID: 24630411
Discovery of benzimidazole oxazolidinediones as novel and selective nonsteroidal mineralocorticoid receptor antagonists.
Yang C, Balsells J, Chu HD, Cox JM, Crespo A, Ma X, Contino L, Brown P, Gao S, Zamlynny B, Wiltsie J, Clemas J, Lisnock J, Gibson J, Zhou G, Garcia-Calvo M, Bateman TJ, Tong V, Xu L, Crook M, Sinclair P, Shen HC. Yang C, et al. Among authors: crook m. ACS Med Chem Lett. 2015 Mar 6;6(4):461-5. doi: 10.1021/acsmedchemlett.5b00010. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941555 Free PMC article.
Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonists.
Ogawa AK, Bunte EV, Mal R, Lan P, Sun Z, Crespo A, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Jochnowitz N, Ma X, Pan Y, Brown P, Zamlynny B, Bateman T, Leung D, Xu L, Tong X, Liu K, Crook M, Sinclair P. Ogawa AK, et al. Among authors: crook m. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2866-2869. doi: 10.1016/j.bmcl.2016.04.052. Epub 2016 Apr 20. Bioorg Med Chem Lett. 2016. PMID: 27161805
Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension.
Zhou X, Crook MF, Sharif-Rodriguez W, Zhu Y, Ruben Z, Pan Y, Urosevic-Price O, Wang L, Flattery AM, Forrest G, Szeto D, Zhao H, Roy S, Forrest MJ. Zhou X, et al. Among authors: crook mf. Clin Exp Hypertens. 2011;33(8):538-47. doi: 10.3109/10641963.2011.566956. Epub 2011 Sep 27. Clin Exp Hypertens. 2011. PMID: 21950654 Free PMC article.
Observation of negative surface and interface energies of quantum dots.
Calvin JJ, Brewer AS, Crook MF, Kaufman TM, Alivisatos AP. Calvin JJ, et al. Among authors: crook mf. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2307633121. doi: 10.1073/pnas.2307633121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648471
Lipid clinic experience with bempedoic acid in three UK centres.
Jakubowska A, Al Hasani W, Williams J, MacMahon Z, Balbas B, Crook MA, Viljoen A, Reynolds TM, Wierzbicki AS. Jakubowska A, et al. Among authors: crook ma. Curr Med Res Opin. 2024 Apr 25:1-6. doi: 10.1080/03007995.2024.2341870. Online ahead of print. Curr Med Res Opin. 2024. PMID: 38616695
Dorsal motor vagal neurons can elicit bradycardia and reduce anxiety-like behavior.
Strain MM, Conley NJ, Kauffman LS, Espinoza L, Fedorchak S, Martinez PC, Crook ME, Jalil M, Hodes GE, Abbott SBG, Güler AD, Campbell JN, Boychuk CR. Strain MM, et al. Among authors: crook me. iScience. 2024 Feb 6;27(3):109137. doi: 10.1016/j.isci.2024.109137. eCollection 2024 Mar 15. iScience. 2024. PMID: 38420585 Free PMC article.
357 results