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Partial freezing of rat livers extends preservation time by 5-fold.
Tessier SN, de Vries RJ, Pendexter CA, Cronin SEJ, Ozer S, Hafiz EOA, Raigani S, Oliveira-Costa JP, Wilks BT, Lopera Higuita M, van Gulik TM, Usta OB, Stott SL, Yeh H, Yarmush ML, Uygun K, Toner M. Tessier SN, et al. Among authors: cronin sej. Nat Commun. 2022 Jul 15;13(1):4008. doi: 10.1038/s41467-022-31490-2. Nat Commun. 2022. PMID: 35840553 Free PMC article.
Supercooling extends preservation time of human livers.
de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K. de Vries RJ, et al. Among authors: cronin sej. Nat Biotechnol. 2019 Oct;37(10):1131-1136. doi: 10.1038/s41587-019-0223-y. Epub 2019 Sep 9. Nat Biotechnol. 2019. PMID: 31501557 Free PMC article.
Cell release during perfusion reflects cold ischemic injury in rat livers.
de Vries RJ, Pendexter CA, Cronin SEJ, Marques B, Hafiz EOA, Muzikansky A, van Gulik TM, Markmann JF, Stott SL, Yeh H, Toner M, Uygun K, Tessier SN. de Vries RJ, et al. Among authors: cronin sej. Sci Rep. 2020 Jan 24;10(1):1102. doi: 10.1038/s41598-020-57589-4. Sci Rep. 2020. PMID: 31980677 Free PMC article.
Subzero non-frozen preservation of human livers in the supercooled state.
de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K. de Vries RJ, et al. Among authors: cronin sej. Nat Protoc. 2020 Jun;15(6):2024-2040. doi: 10.1038/s41596-020-0319-3. Epub 2020 May 20. Nat Protoc. 2020. PMID: 32433625 Free PMC article.
Twenty-four hour ex-vivo normothermic machine perfusion in rat livers.
Haque O, Pendexter CA, Cronin SEJ, Raigani S, de Vries RJ, Yeh H, Markmann JF, Uygun K. Haque O, et al. Among authors: cronin sej. Technology (Singap World Sci). 2020 Mar-Jun;8(1-2):27-36. doi: 10.1142/s2339547820500028. Epub 2020 Nov 5. Technology (Singap World Sci). 2020. PMID: 34307768 Free PMC article.
Zebrafish as a high throughput model for organ preservation and transplantation research.
Da Silveira Cavalcante L, Lopera Higuita M, González-Rosa JM, Marques B, To S, Pendexter CA, Cronin SEJ, Gopinathan K, de Vries RJ, Ellett F, Uygun K, Langenau DM, Toner M, Tessier SN. Da Silveira Cavalcante L, et al. Among authors: cronin sej. FASEB J. 2023 Oct;37(10):e23187. doi: 10.1096/fj.202300076R. FASEB J. 2023. PMID: 37718489
Acellular Perfusate is an Adequate Alternative to Packed Red Blood Cells During Normothermic Human Kidney Perfusion.
Longchamp A, Fontan FM, Aburawi MM, Eymard C, Karimian N, Detelich D, Pendexter C, Cronin S, Agius T, Nagpal S, Banik PD, Tessier SN, Ozer S, Delmonico FL, Uygun K, Yeh H, Markmann JF. Longchamp A, et al. Transplant Direct. 2024 Mar 12;10(4):e1609. doi: 10.1097/TXD.0000000000001609. eCollection 2024 Apr. Transplant Direct. 2024. PMID: 38481967 Free PMC article.