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Sphingolipids in Alzheimer's disease, how can we target them?
Crivelli SM, Giovagnoni C, Visseren L, Scheithauer AL, de Wit N, den Hoedt S, Losen M, Mulder MT, Walter J, de Vries HE, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Adv Drug Deliv Rev. 2020;159:214-231. doi: 10.1016/j.addr.2019.12.003. Epub 2020 Jan 3. Adv Drug Deliv Rev. 2020. PMID: 31911096 Review.
Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.
den Hoedt S, Janssen CIF, Astarita G, Piomelli D, Leijten FPJ, Crivelli SM, Verhoeven AJM, de Vries HE, Walter J, Martinez-Martinez P, Sijbrands EJG, Kiliaan AJ, Mulder MT. den Hoedt S, et al. Among authors: crivelli sm. J Alzheimers Dis. 2017;60(3):769-781. doi: 10.3233/JAD-160739. J Alzheimers Dis. 2017. PMID: 28035926
Visualization of Ceramide-Associated Proteins in Ceramide-Rich Platforms Using a Cross-Linkable Ceramide Analog and Proximity Ligation Assays With Anti-ceramide Antibody.
Jiang X, Zhu Z, Qin H, Tripathi P, Zhong L, Elsherbini A, Karki S, Crivelli SM, Zhi W, Wang G, Spassieva SD, Bieberich E. Jiang X, et al. Among authors: crivelli sm. Front Cell Dev Biol. 2019 Aug 16;7:166. doi: 10.3389/fcell.2019.00166. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31475148 Free PMC article.
Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity.
Elsherbini A, Kirov AS, Dinkins MB, Wang G, Qin H, Zhu Z, Tripathi P, Crivelli SM, Bieberich E. Elsherbini A, et al. Among authors: crivelli sm. Acta Neuropathol Commun. 2020 Apr 28;8(1):60. doi: 10.1186/s40478-020-00931-8. Acta Neuropathol Commun. 2020. PMID: 32345374 Free PMC article.
In vivo evidence of exosome-mediated Aβ neurotoxicity.
Elsherbini A, Qin H, Zhu Z, Tripathi P, Crivelli SM, Bieberich E. Elsherbini A, et al. Among authors: crivelli sm. Acta Neuropathol Commun. 2020 Jul 6;8(1):100. doi: 10.1186/s40478-020-00981-y. Acta Neuropathol Commun. 2020. PMID: 32631455 Free PMC article. No abstract available.
Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Crivelli SM, van Kruining D, Luo Q, Stevens JAA, Giovagnoni C, Paulus A, Bauwens M, Berkes D, de Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Mottaghy FM, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Sci Rep. 2020 Nov 9;10(1):19354. doi: 10.1038/s41598-020-76335-4. Sci Rep. 2020. PMID: 33168861 Free PMC article.
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