Cristea IM - Search Results

1

IFI16 phase separation via multi-phosphorylation drives innate immune signaling.

Liu D, Lum KK, Treen N, Núñez CT, Yang J, Howard TR, Levine M, Cristea IM. Liu D, et al. Among authors: cristea im. Nucleic Acids Res. 2023 Jul 21;51(13):6819-6840. doi: 10.1093/nar/gkad449. Nucleic Acids Res. 2023. PMID: 37283074 Free PMC article.

2

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

Diner BA, Lum KK, Javitt A, Cristea IM. Diner BA, et al. Among authors: cristea im. Mol Cell Proteomics. 2015 Sep;14(9):2341-56. doi: 10.1074/mcp.M114.047068. Epub 2015 Feb 18. Mol Cell Proteomics. 2015. PMID: 25693804 Free PMC article.

3

The emerging role of nuclear viral DNA sensors.

Diner BA, Lum KK, Cristea IM. Diner BA, et al. Among authors: cristea im. J Biol Chem. 2015 Oct 30;290(44):26412-21. doi: 10.1074/jbc.R115.652289. Epub 2015 Sep 9. J Biol Chem. 2015. PMID: 26354430 Free PMC article. Review.

4

Proteomic approaches to uncovering virus-host protein interactions during the progression of viral infection.

Lum KK, Cristea IM. Lum KK, et al. Among authors: cristea im. Expert Rev Proteomics. 2016;13(3):325-40. doi: 10.1586/14789450.2016.1147353. Expert Rev Proteomics. 2016. PMID: 26817613 Free PMC article. Review.

5

Diverse mechanisms evolved by DNA viruses to inhibit early host defenses.

Crow MS, Lum KK, Sheng X, Song B, Cristea IM. Crow MS, et al. Among authors: cristea im. Crit Rev Biochem Mol Biol. 2016 Nov/Dec;51(6):452-481. doi: 10.1080/10409238.2016.1226250. Epub 2016 Sep 21. Crit Rev Biochem Mol Biol. 2016. PMID: 27650455 Free PMC article. Review.

6

Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.

Diner BA, Lum KK, Toettcher JE, Cristea IM. Diner BA, et al. Among authors: cristea im. mBio. 2016 Nov 15;7(6):e01553-16. doi: 10.1128/mBio.01553-16. mBio. 2016. PMID: 27935834 Free PMC article.

7

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

Lum KK, Song B, Federspiel JD, Diner BA, Howard T, Cristea IM. Lum KK, et al. Among authors: cristea im. Cell Syst. 2018 Dec 26;7(6):627-642.e6. doi: 10.1016/j.cels.2018.10.010. Epub 2018 Nov 21. Cell Syst. 2018. PMID: 30471916 Free PMC article.

8

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

Federspiel JD, Greco TM, Lum KK, Cristea IM. Federspiel JD, et al. Among authors: cristea im. Mol Cell Proteomics. 2019 Aug 9;18(8 suppl 1):S92-S113. doi: 10.1074/mcp.RA118.001253. Epub 2019 Apr 30. Mol Cell Proteomics. 2019. PMID: 31040226 Free PMC article.

9

Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA.

Lum KK, Howard TR, Pan C, Cristea IM. Lum KK, et al. Among authors: cristea im. mBio. 2019 Jul 23;10(4):e01428-19. doi: 10.1128/mBio.01428-19. mBio. 2019. PMID: 31337724 Free PMC article.

10

Workflows and considerations for investigating protein interactions of viral DNA sensors.

Howard TR, Song B, Cristea IM. Howard TR, et al. Among authors: cristea im. Methods Enzymol. 2019;625:309-338. doi: 10.1016/bs.mie.2019.04.026. Epub 2019 May 20. Methods Enzymol. 2019. PMID: 31455534 Free PMC article.

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