Crichlow GV - Search Results

1

ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.

Ioannou K, Cheng KF, Crichlow GV, Birmpilis AI, Lolis EJ, Tsitsilonis OE, Al-Abed Y. Ioannou K, et al. Among authors: crichlow gv. Int J Oncol. 2014 Oct;45(4):1457-68. doi: 10.3892/ijo.2014.2551. Epub 2014 Jul 22. Int J Oncol. 2014. PMID: 25050663 Free PMC article.

2

Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates.

Crichlow GV, Fan C, Keeler C, Hodsdon M, Lolis EJ. Crichlow GV, et al. Biochemistry. 2012 Sep 25;51(38):7506-14. doi: 10.1021/bi3005494. Epub 2012 Sep 11. Biochemistry. 2012. PMID: 22931430 Free PMC article.

3

Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.

Crichlow GV, Cheng KF, Dabideen D, Ochani M, Aljabari B, Pavlov VA, Miller EJ, Lolis E, Al-Abed Y. Crichlow GV, et al. J Biol Chem. 2007 Aug 10;282(32):23089-95. doi: 10.1074/jbc.M701825200. Epub 2007 May 25. J Biol Chem. 2007. PMID: 17526494 Free PMC article.

4

A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.

Winner M, Meier J, Zierow S, Rendon BE, Crichlow GV, Riggs R, Bucala R, Leng L, Smith N, Lolis E, Trent JO, Mitchell RA. Winner M, et al. Among authors: crichlow gv. Cancer Res. 2008 Sep 15;68(18):7253-7. doi: 10.1158/0008-5472.CAN-07-6227. Cancer Res. 2008. PMID: 18794110 Free PMC article.

5

Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.

Crichlow GV, Lubetsky JB, Leng L, Bucala R, Lolis EJ. Crichlow GV, et al. Biochemistry. 2009 Jan 13;48(1):132-9. doi: 10.1021/bi8014423. Biochemistry. 2009. PMID: 19090677 Free PMC article.

6

Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.

Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Cho Y, et al. Among authors: crichlow gv. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. doi: 10.1073/pnas.1002716107. Epub 2010 Jun 8. Proc Natl Acad Sci U S A. 2010. PMID: 20534506 Free PMC article.

7

Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.

Hsiao HT, Crichlow GV, Murphy JW, Folta-Stogniew EJ, Lolis EJ, Braddock DT. Hsiao HT, et al. Among authors: crichlow gv. PLoS One. 2020 Nov 30;15(11):e0242725. doi: 10.1371/journal.pone.0242725. eCollection 2020. PLoS One. 2020. PMID: 33253191 Free PMC article.

8

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.

Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D. Crichlow GV, et al. EMBO J. 2008 Jan 9;27(1):277-89. doi: 10.1038/sj.emboj.7601936. Epub 2007 Dec 6. EMBO J. 2008. PMID: 18059478 Free PMC article.

9

Protein crystallization facilitated by molecularly imprinted polymers.

Saridakis E, Khurshid S, Govada L, Phan Q, Hawkins D, Crichlow GV, Lolis E, Reddy SM, Chayen NE. Saridakis E, et al. Among authors: crichlow gv. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11081-6. doi: 10.1073/pnas.1016539108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690356 Free PMC article.

10

Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion.

Crichlow GV, Kuzin AP, Nukaga M, Mayama K, Sawai T, Knox JR. Crichlow GV, et al. Biochemistry. 1999 Aug 10;38(32):10256-61. doi: 10.1021/bi9908787. Biochemistry. 1999. PMID: 10441119

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