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Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV - Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial.
Compagnucci A, Chan MK, Saïdi Y, Cressey TR, Bamford A, Riault Y, Coelho A, Nolan A, Chalermpantmetagul S, Morkunaite G, Amuge P, Musiime V, Violari A, Cotton M, Kekitiinwa AR, Kaudha E, Groenewald M, Liberty AA, Kanjanavanit S, Volokha A, Bologna R, Pavia Ruz N, Prieto Tato L, Paioni P, Marques L, Reliquet V, Niehues T, Welch SB, Ford D, Giaquinto C, Gibb DM, Babiker A, Ramos Amador JT; SMILE-PENTA17-ANRS 152 Trial Group. Compagnucci A, et al. Among authors: cressey tr. EClinicalMedicine. 2023 Jun 2;60:102025. doi: 10.1016/j.eclinm.2023.102025. eCollection 2023 Jun. EClinicalMedicine. 2023. PMID: 37304494 Free PMC article.
Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children.
Cressey TR, Green H, Khoo S, Treluyer JM, Compagnucci A, Saidi Y, Lallemant M, Gibb DM, Burger DM; Paediatric European Network for Treatment of AIDS II Study Group. Cressey TR, et al. Clin Infect Dis. 2008 May 15;46(10):1601-8. doi: 10.1086/587657. Clin Infect Dis. 2008. PMID: 18419497 Free PMC article. Clinical Trial.
Abacavir Drug Exposures in African Children Under 14 kg Using Pediatric Solid Fixed Dose Combinations According to World Health Organization Weight Bands.
Chupradit S, Wamalwa DC, Maleche-Obimbo E, Kekitiinwa AR, Mwanga-Amumpaire J, Bukusi EA, Nyandiko WM, Mbuthia JK, Swanson A; DNDi Clinical Team; Cressey TR, Punyawudho B, Musiime V. Chupradit S, et al. Among authors: cressey tr. J Pediatric Infect Dis Soc. 2023 Nov 30;12(11):574-580. doi: 10.1093/jpids/piad082. J Pediatric Infect Dis Soc. 2023. PMID: 37798141 Free PMC article.
Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial.
Abdalla S, Compagnucci A, Riault Y, Chan MK, Bamford A, Nolan A, Ramos JT, Constant V, Nguyen T-N, Zheng Y, Tréluyer J-M, Froelicher-Bournaud L, Neveux N, Saidi Y, Cressey TR, Hirt D; SMILE study group. Abdalla S, et al. Among authors: cressey tr. Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0100423. doi: 10.1128/aac.01004-23. Epub 2023 Dec 11. Antimicrob Agents Chemother. 2024. PMID: 38092664 Free PMC article.
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries.
Kakaraskoska Boceska B, Vilken T, Xavier BB, Kostyanev T, Lin Q, Lammens C, Ellis S, O'Brien S, da Costa RMA, Cook A, Russell N, Bielicki J, Riddell A, Stohr W, Walker AS, Berezin EN, Roilides E, De Luca M, Romani L, Ballot D, Dramowski A, Wadula J, Lochindarat S, Boonkasidecha S, Namiiro F, Ngoc HTB, Tran MD, Cressey TR, Preedisripipat K, Berkley JA, Musyimi R, Zarras C, Nana T, Whitelaw A, da Silva CB, Jaglal P, Ssengooba W, Saha SK, Islam MS, Mussi-Pinhata MM, Carvalheiro CG, Piddock LJV, Heath PT, Malhotra-Kumar S, Sharland M, Glupczynski Y, Goossens H. Kakaraskoska Boceska B, et al. Among authors: cressey tr. Nat Commun. 2024 May 10;15(1):3947. doi: 10.1038/s41467-024-48296-z. Nat Commun. 2024. PMID: 38729951 Free PMC article.
D3/Penta 21 clinical trial design: A randomised non-inferiority trial with nested drug licensing substudy to assess dolutegravir and lamivudine fixed dose formulations for the maintenance of virological suppression in children with HIV-1 infection, aged 2 to 15 years.
Turkova A, Chan MK, Kityo C, Kekitiinwa AR, Musoke P, Violari A, Variava E, Archary M, Cressey TR, Chalermpantmetagul S, Sawasdichai K, Ounchanum P, Kanjanavanit S, Srirojana S, Srirompotong U, Welch S, Bamford A, Epalza C, Fortuny C, Colbers A, Nastouli E, Walker S, Carr D, Conway M, Spyer MJ, Parkar N, White I, Nardone A, Thomason MJ, Ferrand RA, Giaquinto C, Ford D; D3 trial team. Turkova A, et al. Among authors: cressey tr. Contemp Clin Trials. 2024 Apr 16;142:107540. doi: 10.1016/j.cct.2024.107540. Online ahead of print. Contemp Clin Trials. 2024. PMID: 38636725 Free article.
A pilot program of HIV pre-exposure prophylaxis in Thai youth.
Rungmaitree S, Werarak P, Pumpradit W, Phongsamart W, Lapphra K, Wittawatmongkol O, Durier Y, Maleesatharn A, Kuttiparambil B, Cressey TR, Hoffman RM, Chokephaibulkit K. Rungmaitree S, et al. Among authors: cressey tr. PLoS One. 2024 Feb 22;19(2):e0298914. doi: 10.1371/journal.pone.0298914. eCollection 2024. PLoS One. 2024. PMID: 38386680 Free PMC article.
Paediatric abacavir-lamivudine fixed-dose dispersible tablets and ritonavir-boosted lopinavir granules in neonates exposed to HIV (PETITE study): an open-label, two-stage, single-arm, phase 1/2, pharmacokinetic and safety trial.
Bekker A, Salvadori N, Rabie H, du Toit S, Than-In-At K, Groenewald M, Cressey R, Nielsen J, Capparelli EV, Lallemant M, Cotton MF, Cressey TR; PETITE-ABC/3TC-LPVr Study Team. Bekker A, et al. Among authors: cressey tr. Lancet HIV. 2024 Feb;11(2):e86-e95. doi: 10.1016/S2352-3018(23)00289-8. Lancet HIV. 2024. PMID: 38296364 Clinical Trial.
157 results