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Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma.
Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli-de la Forest Divonne S, Veber R, Petti L, Bourdely P, Mörgelin M, Brauchle EM, Cremel G, Randrianarisoa V, Camara A, Rekima S, Schaub S, Nouhen K, Imhof T, Hansen U, Paul N, Carapito R, Pythoud N, Hirschler A, Carapito C, Dumortier H, Mueller CG, Koch M, Schenke-Layland K, Kon S, Sudaka A, Anjuère F, Van Obberghen-Schilling E, Orend G. Spenlé C, et al. Among authors: cremel g. Cancer Immunol Res. 2020 Sep;8(9):1122-1138. doi: 10.1158/2326-6066.CIR-20-0074. Epub 2020 Jul 14. Cancer Immunol Res. 2020. PMID: 32665262 Free article.
Tenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression.
Murdamoothoo D, Sun Z, Yilmaz A, Riegel G, Abou-Faycal C, Deligne C, Velazquez-Quesada I, Erne W, Nascimento M, Mörgelin M, Cremel G, Paul N, Carapito R, Veber R, Dumortier H, Yuan J, Midwood KS, Loustau T, Orend G. Murdamoothoo D, et al. Among authors: cremel g. EMBO Mol Med. 2021 Jun 7;13(6):e13270. doi: 10.15252/emmm.202013270. Epub 2021 May 14. EMBO Mol Med. 2021. PMID: 33988305 Free PMC article.
Modulating tenascin-C functions by targeting the MAtrix REgulating MOtif, "MAREMO".
Loustau T, Abou-Faycal C, Erne W, Zur Wiesch PA, Ksouri A, Imhof T, Mörgelin M, Li C, Mathieu M, Salomé N, Crémel G, Dhaouadi S, Bouhaouala-Zahar B, Koch M, Orend G. Loustau T, et al. Among authors: cremel g. Matrix Biol. 2022 Apr;108:20-38. doi: 10.1016/j.matbio.2022.02.007. Epub 2022 Feb 26. Matrix Biol. 2022. PMID: 35227929
Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model.
Saupe F, Schwenzer A, Jia Y, Gasser I, Spenlé C, Langlois B, Kammerer M, Lefebvre O, Hlushchuk R, Rupp T, Marko M, van der Heyden M, Cremel G, Arnold C, Klein A, Simon-Assmann P, Djonov V, Neuville-Méchine A, Esposito I, Slotta-Huspenina J, Janssen KP, de Wever O, Christofori G, Hussenet T, Orend G. Saupe F, et al. Among authors: cremel g. Cell Rep. 2013 Oct 31;5(2):482-92. doi: 10.1016/j.celrep.2013.09.014. Epub 2013 Oct 17. Cell Rep. 2013. PMID: 24139798 Free article.
Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma.
Mammadova-Bach E, Rupp T, Spenlé C, Jivkov I, Shankaranarayanan P, Klein A, Pisarsky L, Méchine-Neuville A, Cremel G, Kedinger M, De Wever O, Ambartsumian N, Robine S, Pencreach E, Guenot D, Simon-Assmann P, Goetz JG, Orend G, Lefebvre O. Mammadova-Bach E, et al. Among authors: cremel g. Biol Cell. 2018 Jun 15. doi: 10.1111/boc.201800007. Online ahead of print. Biol Cell. 2018. PMID: 29907957
Transmembrane domain targeting peptide antagonizing ErbB2/Neu inhibits breast tumor growth and metastasis.
Arpel A, Sawma P, Spenlé C, Fritz J, Meyer L, Garnier N, Velázquez-Quesada I, Hussenet T, Aci-Sèche S, Baumlin N, Genest M, Brasse D, Hubert P, Crémel G, Orend G, Laquerrière P, Bagnard D. Arpel A, et al. Among authors: cremel g. Cell Rep. 2014 Sep 25;8(6):1714-1721. doi: 10.1016/j.celrep.2014.07.044. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220456 Free article.
Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide.
Jacob L, Sawma P, Garnier N, Meyer LA, Fritz J, Hussenet T, Spenlé C, Goetz J, Vermot J, Fernandez A, Baumlin N, Aci-Sèche S, Orend G, Roussel G, Crémel G, Genest M, Hubert P, Bagnard D. Jacob L, et al. Among authors: cremel g. Oncotarget. 2016 Sep 6;7(36):57851-57865. doi: 10.18632/oncotarget.11072. Oncotarget. 2016. PMID: 27506939 Free PMC article.
64 results