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Page 1
Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, Kaymak I, Lau KH, Kelly DP, Puchalska P, Williams KS, Krawczyk CM, Lévesque D, Boisvert FM, Sheldon RD, Rothbart SB, Crawford PA, Jones RG. Luda KM, et al. Among authors: crawford pa. Immunity. 2023 Sep 12;56(9):2021-2035.e8. doi: 10.1016/j.immuni.2023.07.002. Epub 2023 Jul 28. Immunity. 2023. PMID: 37516105 Free article.
Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice.
Rome FI, Shobert GL, Voigt WC, Stagg DB, Puchalska P, Burgess SC, Crawford PA, Hughey CC. Rome FI, et al. Among authors: crawford pa. Am J Physiol Endocrinol Metab. 2023 Jan 1;324(1):E9-E23. doi: 10.1152/ajpendo.00222.2022. Epub 2022 Nov 9. Am J Physiol Endocrinol Metab. 2023. PMID: 36351254 Free PMC article.
Mitochondrial citrate metabolism and efflux regulate BeWo differentiation.
Mahr RM, Jena S, Nashif SK, Nelson AB, Rauckhorst AJ, Rome FI, Sheldon RD, Hughey CC, Puchalska P, Gearhart MD, Taylor EB, Crawford PA, Wernimont SA. Mahr RM, et al. Among authors: crawford pa. Sci Rep. 2023 May 6;13(1):7387. doi: 10.1038/s41598-023-34435-x. Sci Rep. 2023. PMID: 37149697 Free PMC article.
Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner.
Nashif SK, Mahr RM, Jena S, Jo S, Nelson AB, Sadowski D, Crawford PA, Puchalska P, Alejandro EU, Gearhart MD, Wernimont SA. Nashif SK, et al. Among authors: crawford pa. Front Cell Dev Biol. 2023 May 12;11:1167097. doi: 10.3389/fcell.2023.1167097. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37250894 Free PMC article.
Ketone bodies in right ventricular failure: A unique therapeutic opportunity.
Blake M, Puchalska P, Kazmirczak F, Blake J, Moon R, Thenappan T, Crawford PA, Prins KW. Blake M, et al. Among authors: crawford pa. Heliyon. 2023 Nov 15;9(11):e22227. doi: 10.1016/j.heliyon.2023.e22227. eCollection 2023 Nov. Heliyon. 2023. PMID: 38058654 Free PMC article.
Metabolic Messengers: ketone bodies.
Nelson AB, Queathem ED, Puchalska P, Crawford PA. Nelson AB, et al. Among authors: crawford pa. Nat Metab. 2023 Dec;5(12):2062-2074. doi: 10.1038/s42255-023-00935-3. Epub 2023 Dec 13. Nat Metab. 2023. PMID: 38092961 Review.
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase.
Mechchate H, Abdualkader AM, Bernacchi JB, Gopal K, Tabatabaei Dakhili SA, Yang K, Greenwell AA, Kong X, Crawford PA, Al Batran R. Mechchate H, et al. Among authors: crawford pa. Am J Physiol Endocrinol Metab. 2023 May 1;324(5):E425-E436. doi: 10.1152/ajpendo.00206.2022. Epub 2023 Mar 29. Am J Physiol Endocrinol Metab. 2023. PMID: 36989424 Free article.
98 results