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Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy.
Prokopi A, Tripp CH, Tummers B, Hornsteiner F, Spoeck S, Crawford JC, Clements DR, Efremova M, Hutter K, Bellmann L, Cappellano G, Cadilha BL, Kobold S, Boon L, Ortner D, Trajanoski Z, Chen S, de Gruijl TD, Idoyaga J, Green DR, Stoitzner P. Prokopi A, et al. Among authors: crawford jc. J Immunother Cancer. 2021 Jan;9(1):e000832. doi: 10.1136/jitc-2020-000832. J Immunother Cancer. 2021. PMID: 33408092 Free PMC article.
LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.
Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, Green DR. Cunha LD, et al. Among authors: crawford jc. Cell. 2018 Oct 4;175(2):429-441.e16. doi: 10.1016/j.cell.2018.08.061. Epub 2018 Sep 20. Cell. 2018. PMID: 30245008 Free PMC article.
To the edge of cell death and back.
Gong YN, Crawford JC, Heckmann BL, Green DR. Gong YN, et al. Among authors: crawford jc. FEBS J. 2019 Feb;286(3):430-440. doi: 10.1111/febs.14714. Epub 2018 Dec 19. FEBS J. 2019. PMID: 30506628 Free PMC article. Review.
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG. Zamora AE, et al. Among authors: crawford jc. Sci Transl Med. 2019 Jun 26;11(498):eaat8549. doi: 10.1126/scitranslmed.aat8549. Sci Transl Med. 2019. PMID: 31243155 Free PMC article.
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, Xu Y, Upton JW, Thomas PG, Green DR, Balachandran S. Zhang T, et al. Among authors: crawford jc. Cell. 2020 Mar 19;180(6):1115-1129.e13. doi: 10.1016/j.cell.2020.02.050. Cell. 2020. PMID: 32200799 Free PMC article.
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Tummers B, Mari L, Guy CS, Heckmann BL, Rodriguez DA, Rühl S, Moretti J, Crawford JC, Fitzgerald P, Kanneganti TD, Janke LJ, Pelletier S, Blander JM, Green DR. Tummers B, et al. Among authors: crawford jc. Immunity. 2020 Jun 16;52(6):994-1006.e8. doi: 10.1016/j.immuni.2020.04.010. Epub 2020 May 18. Immunity. 2020. PMID: 32428502 Free PMC article.
Sublethal cytochrome c release generates drug-tolerant persister cells.
Kalkavan H, Chen MJ, Crawford JC, Quarato G, Fitzgerald P, Tait SWG, Goding CR, Green DR. Kalkavan H, et al. Among authors: crawford jc. Cell. 2022 Sep 1;185(18):3356-3374.e22. doi: 10.1016/j.cell.2022.07.025. Cell. 2022. PMID: 36055199 Free PMC article.
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Rodriguez DA, Quarato G, Liedmann S, Tummers B, Zhang T, Guy C, Crawford JC, Palacios G, Pelletier S, Kalkavan H, Shaw JJP, Fitzgerald P, Chen MJ, Balachandran S, Green DR. Rodriguez DA, et al. Among authors: crawford jc. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2207240119. doi: 10.1073/pnas.2207240119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191211 Free PMC article.
92 results