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Arginase 1 is a key driver of immune suppression in pancreatic cancer.
Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M. Menjivar RE, et al. Among authors: crawford hc. Elife. 2023 Feb 2;12:e80721. doi: 10.7554/eLife.80721. Elife. 2023. PMID: 36727849 Free PMC article.
Identification and manipulation of biliary metaplasia in pancreatic tumors.
Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC. Delgiorno KE, et al. Among authors: crawford hc. Gastroenterology. 2014 Jan;146(1):233-44.e5. doi: 10.1053/j.gastro.2013.08.053. Epub 2013 Aug 30. Gastroenterology. 2014. PMID: 23999170 Free PMC article.
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu CY, Carpenter ES, Takeuchi KK, Halbrook CJ, Peverley LV, Bien H, Hall JC, DelGiorno KE, Pal D, Song Y, Shi C, Lin RZ, Crawford HC. Wu CY, et al. Among authors: crawford hc. Gastroenterology. 2014 Dec;147(6):1405-16.e7. doi: 10.1053/j.gastro.2014.08.032. Epub 2014 Aug 27. Gastroenterology. 2014. PMID: 25311989 Free PMC article.
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC. Roy N, et al. Among authors: crawford hc. Genes Dev. 2016 Dec 15;30(24):2669-2683. doi: 10.1101/gad.291021.116. Genes Dev. 2016. PMID: 28087712 Free PMC article.
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. Abel EV, et al. Among authors: crawford hc. Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947. Elife. 2018. PMID: 30074477 Free PMC article.
Epithelial-Stromal Interactions in Pancreatic Cancer.
Zhang Y, Crawford HC, Pasca di Magliano M. Zhang Y, et al. Among authors: crawford hc. Annu Rev Physiol. 2019 Feb 10;81:211-233. doi: 10.1146/annurev-physiol-020518-114515. Epub 2018 Nov 12. Annu Rev Physiol. 2019. PMID: 30418798 Review.
Spatial and phenotypic immune profiling of metastatic colon cancer.
Lazarus J, Maj T, Smith JJ, Perusina Lanfranca M, Rao A, D'Angelica MI, Delrosario L, Girgis A, Schukow C, Shia J, Kryczek I, Shi J, Wasserman I, Crawford H, Nathan H, Pasca Di Magliano M, Zou W, Frankel TL. Lazarus J, et al. JCI Insight. 2018 Nov 15;3(22):e121932. doi: 10.1172/jci.insight.121932. JCI Insight. 2018. PMID: 30429368 Free PMC article.
144 results