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Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Kemp SB, Steele NG, Carpenter ES, Donahue KL, Bushnell GG, Morris AH, The S, Orbach SM, Sirihorachai VR, Nwosu ZC, Espinoza C, Lima F, Brown K, Girgis AA, Gunchick V, Zhang Y, Lyssiotis CA, Frankel TL, Bednar F, Rao A, Sahai V, Shea LD, Crawford HC, Pasca di Magliano M. Kemp SB, et al. Among authors: crawford hc. Life Sci Alliance. 2021 Mar 29;4(6):e202000935. doi: 10.26508/lsa.202000935. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33782087 Free PMC article.
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu CY, Carpenter ES, Takeuchi KK, Halbrook CJ, Peverley LV, Bien H, Hall JC, DelGiorno KE, Pal D, Song Y, Shi C, Lin RZ, Crawford HC. Wu CY, et al. Among authors: crawford hc. Gastroenterology. 2014 Dec;147(6):1405-16.e7. doi: 10.1053/j.gastro.2014.08.032. Epub 2014 Aug 27. Gastroenterology. 2014. PMID: 25311989 Free PMC article.
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. Abel EV, et al. Among authors: crawford hc. Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947. Elife. 2018. PMID: 30074477 Free PMC article.
Epithelial-Stromal Interactions in Pancreatic Cancer.
Zhang Y, Crawford HC, Pasca di Magliano M. Zhang Y, et al. Among authors: crawford hc. Annu Rev Physiol. 2019 Feb 10;81:211-233. doi: 10.1146/annurev-physiol-020518-114515. Epub 2018 Nov 12. Annu Rev Physiol. 2019. PMID: 30418798 Review.
Spatial and phenotypic immune profiling of metastatic colon cancer.
Lazarus J, Maj T, Smith JJ, Perusina Lanfranca M, Rao A, D'Angelica MI, Delrosario L, Girgis A, Schukow C, Shia J, Kryczek I, Shi J, Wasserman I, Crawford H, Nathan H, Pasca Di Magliano M, Zou W, Frankel TL. Lazarus J, et al. JCI Insight. 2018 Nov 15;3(22):e121932. doi: 10.1172/jci.insight.121932. JCI Insight. 2018. PMID: 30429368 Free PMC article.
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, Chang D, Biankin A, Shi J, Frankel TL, Crawford HC, Morton JP, Pasca di Magliano M, Lyssiotis CA. Halbrook CJ, et al. Among authors: crawford hc. Cell Metab. 2019 Jun 4;29(6):1390-1399.e6. doi: 10.1016/j.cmet.2019.02.001. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827862 Free PMC article.
Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis.
Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC. Wen HJ, et al. Among authors: crawford hc. Cell Mol Gastroenterol Hepatol. 2019;8(2):173-192. doi: 10.1016/j.jcmgh.2019.05.006. Epub 2019 May 21. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31125624 Free PMC article.
148 results