Crawford GE - Search Results

1

Targeted long-read sequencing identifies missing disease-causing variation.

Miller DE, Sulovari A, Wang T, Loucks H, Hoekzema K, Munson KM, Lewis AP, Fuerte EPA, Paschal CR, Walsh T, Thies J, Bennett JT, Glass I, Dipple KM, Patterson K, Bonkowski ES, Nelson Z, Squire A, Sikes M, Beckman E, Bennett RL, Earl D, Lee W, Allikmets R, Perlman SJ, Chow P, Hing AV, Wenger TL, Adam MP, Sun A, Lam C, Chang I, Zou X, Austin SL, Huggins E, Safi A, Iyengar AK, Reddy TE, Majoros WH, Allen AS, Crawford GE, Kishnani PS; University of Washington Center for Mendelian Genomics; King MC, Cherry T, Chong JX, Bamshad MJ, Nickerson DA, Mefford HC, Doherty D, Eichler EE. Miller DE, et al. Among authors: crawford ge. Am J Hum Genet. 2021 Aug 5;108(8):1436-1449. doi: 10.1016/j.ajhg.2021.06.006. Epub 2021 Jul 2. Am J Hum Genet. 2021. PMID: 34216551 Free PMC article.

2

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.

Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Among authors: crawford ge. Nat Biotechnol. 2017 Jun;35(6):561-568. doi: 10.1038/nbt.3853. Epub 2017 Apr 3. Nat Biotechnol. 2017. PMID: 28369033 Free PMC article.

3

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.

Polstein LR, Perez-Pinera P, Kocak DD, Vockley CM, Bledsoe P, Song L, Safi A, Crawford GE, Reddy TE, Gersbach CA. Polstein LR, et al. Among authors: crawford ge. Genome Res. 2015 Aug;25(8):1158-69. doi: 10.1101/gr.179044.114. Epub 2015 May 29. Genome Res. 2015. PMID: 26025803 Free PMC article.

4

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.

Vockley CM, D'Ippolito AM, McDowell IC, Majoros WH, Safi A, Song L, Crawford GE, Reddy TE. Vockley CM, et al. Among authors: crawford ge. Cell. 2016 Aug 25;166(5):1269-1281.e19. doi: 10.1016/j.cell.2016.07.049. Cell. 2016. PMID: 27565349 Free PMC article.

5

Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.

Klann TS, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Among authors: crawford ge. Methods Mol Biol. 2018;1767:447-480. doi: 10.1007/978-1-4939-7774-1_25. Methods Mol Biol. 2018. PMID: 29524151

6

Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids.

D'Ippolito AM, McDowell IC, Barrera A, Hong LK, Leichter SM, Bartelt LC, Vockley CM, Majoros WH, Safi A, Song L, Gersbach CA, Crawford GE, Reddy TE. D'Ippolito AM, et al. Among authors: crawford ge. Cell Syst. 2018 Aug 22;7(2):146-160.e7. doi: 10.1016/j.cels.2018.06.007. Epub 2018 Jul 18. Cell Syst. 2018. PMID: 30031775 Free article.

7

Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants.

Lee D, Kapoor A, Safi A, Song L, Halushka MK, Crawford GE, Chakravarti A. Lee D, et al. Among authors: crawford ge. Genome Res. 2018 Oct;28(10):1577-1588. doi: 10.1101/gr.234633.118. Epub 2018 Aug 23. Genome Res. 2018. PMID: 30139769 Free PMC article.

8

Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach.

Edsall LE, Berrio A, Majoros WH, Swain-Lenz D, Morrow S, Shibata Y, Safi A, Wray GA, Crawford GE, Allen AS. Edsall LE, et al. Among authors: crawford ge. Genome Biol Evol. 2019 Oct 1;11(10):3035-3053. doi: 10.1093/gbe/evz218. Genome Biol Evol. 2019. PMID: 31599933 Free PMC article.

9

Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data.

Luo K, Zhong J, Safi A, Hong LK, Tewari AK, Song L, Reddy TE, Ma L, Crawford GE, Hartemink AJ. Luo K, et al. Among authors: crawford ge. Genome Res. 2022 Jun;32(6):1183-1198. doi: 10.1101/gr.272203.120. Epub 2022 May 24. Genome Res. 2022. PMID: 35609992 Free PMC article.

10

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.

Fufa TD, Harris ML, Watkins-Chow DE, Levy D, Gorkin DU, Gildea DE, Song L, Safi A, Crawford GE, Sviderskaya EV, Bennett DC, Mccallion AS, Loftus SK, Pavan WJ. Fufa TD, et al. Among authors: crawford ge. Hum Mol Genet. 2015 Oct 1;24(19):5433-50. doi: 10.1093/hmg/ddv267. Epub 2015 Jul 23. Hum Mol Genet. 2015. PMID: 26206884 Free PMC article.

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