Crawford GE - Search Results

1

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Among authors: crawford ge. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

2

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA. Hilton IB, et al. Among authors: crawford ge. Nat Biotechnol. 2015 May;33(5):510-7. doi: 10.1038/nbt.3199. Epub 2015 Apr 6. Nat Biotechnol. 2015. PMID: 25849900 Free PMC article.

3

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.

Frank CL, Liu F, Wijayatunge R, Song L, Biegler MT, Yang MG, Vockley CM, Safi A, Gersbach CA, Crawford GE, West AE. Frank CL, et al. Among authors: crawford ge. Nat Neurosci. 2015 May;18(5):647-56. doi: 10.1038/nn.3995. Epub 2015 Apr 6. Nat Neurosci. 2015. PMID: 25849986 Free PMC article.

4

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.

Polstein LR, Perez-Pinera P, Kocak DD, Vockley CM, Bledsoe P, Song L, Safi A, Crawford GE, Reddy TE, Gersbach CA. Polstein LR, et al. Among authors: crawford ge. Genome Res. 2015 Aug;25(8):1158-69. doi: 10.1101/gr.179044.114. Epub 2015 May 29. Genome Res. 2015. PMID: 26025803 Free PMC article.

5

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.

Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA. Thakore PI, et al. Among authors: crawford ge. Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26. Nat Methods. 2015. PMID: 26501517 Free PMC article.

6

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.

Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Among authors: crawford ge. Nat Biotechnol. 2017 Jun;35(6):561-568. doi: 10.1038/nbt.3853. Epub 2017 Apr 3. Nat Biotechnol. 2017. PMID: 28369033 Free PMC article.

7

Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.

Klann TS, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Among authors: crawford ge. Methods Mol Biol. 2018;1767:447-480. doi: 10.1007/978-1-4939-7774-1_25. Methods Mol Biol. 2018. PMID: 29524151

8

Synergistic and tunable human gene activation by combinations of synthetic transcription factors.

Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA. Perez-Pinera P, et al. Among authors: crawford ge. Nat Methods. 2013 Mar;10(3):239-42. doi: 10.1038/nmeth.2361. Epub 2013 Feb 3. Nat Methods. 2013. PMID: 23377379 Free PMC article.

9

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.

McDowell IC, Barrera A, D'Ippolito AM, Vockley CM, Hong LK, Leichter SM, Bartelt LC, Majoros WH, Song L, Safi A, Koçak DD, Gersbach CA, Hartemink AJ, Crawford GE, Engelhardt BE, Reddy TE. McDowell IC, et al. Among authors: crawford ge. Genome Res. 2018 Sep;28(9):1272-1284. doi: 10.1101/gr.233346.117. Epub 2018 Aug 10. Genome Res. 2018. PMID: 30097539 Free PMC article.

10

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.

Vockley CM, D'Ippolito AM, McDowell IC, Majoros WH, Safi A, Song L, Crawford GE, Reddy TE. Vockley CM, et al. Among authors: crawford ge. Cell. 2016 Aug 25;166(5):1269-1281.e19. doi: 10.1016/j.cell.2016.07.049. Cell. 2016. PMID: 27565349 Free PMC article.

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