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Anti-Inflammatory Activity and Cheminformatics Analysis of New Poten t 2-Substituted 1-Methyl-5-Nitroindazolinones.
Siverio-Mota D, Andujar I, Marrero-Ponce Y, Giner RM, Diaz-Mendoza C, Paba GM, Vicet-Muro L, Cordero-Maldonado ML, de Witte PAM, Crawford AD, Veitia MS, Perez-Jimenez F, Aran VJ. Siverio-Mota D, et al. Among authors: crawford ad. Curr Top Med Chem. 2018 Feb 9;17(30):3236-3248. doi: 10.2174/1568026618666180119125255. Curr Top Med Chem. 2018. PMID: 29357800 Review.
Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: the nitroindazolinone chemotype.
Marrero-Ponce Y, Siverio-Mota D, Gálvez-Llompart M, Recio MC, Giner RM, García-Domènech R, Torrens F, Arán VJ, Cordero-Maldonado ML, Esguera CV, de Witte PA, Crawford AD. Marrero-Ponce Y, et al. Among authors: crawford ad. Eur J Med Chem. 2011 Dec;46(12):5736-53. doi: 10.1016/j.ejmech.2011.07.053. Epub 2011 Aug 17. Eur J Med Chem. 2011. PMID: 22000935
Integration of Microfractionation, qNMR and zebrafish screening for the in vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products.
Bohni N, Cordero-Maldonado ML, Maes J, Siverio-Mota D, Marcourt L, Munck S, Kamuhabwa AR, Moshi MJ, Esguerra CV, de Witte PA, Crawford AD, Wolfender JL. Bohni N, et al. Among authors: crawford ad. PLoS One. 2013 May 21;8(5):e64006. doi: 10.1371/journal.pone.0064006. Print 2013. PLoS One. 2013. PMID: 23700445 Free PMC article.
Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models.
Buenafe OE, Orellana-Paucar A, Maes J, Huang H, Ying X, De Borggraeve W, Crawford AD, Luyten W, Esguerra CV, de Witte P. Buenafe OE, et al. Among authors: crawford ad. ACS Chem Neurosci. 2013 Nov 20;4(11):1479-87. doi: 10.1021/cn400140e. Epub 2013 Sep 6. ACS Chem Neurosci. 2013. PMID: 23937066 Free PMC article.
80 results