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Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Jamshidiha M, Lanyon-Hogg T, Sutherell CL, Craven GB, Tersa M, De Vita E, Brustur D, Pérez-Dorado I, Hassan S, Petracca R, Morgan RM, Sanz-Hernández M, Norman JC, Armstrong A, Mann DJ, Cota E, Tate EW. Jamshidiha M, et al. Among authors: craven gb. RSC Med Chem. 2021 Dec 16;13(2):150-155. doi: 10.1039/d1md00225b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308027 Free PMC article.
CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery.
Benns HJ, Storch M, Falco JA, Fisher FR, Tamaki F, Alves E, Wincott CJ, Milne R, Wiedemar N, Craven G, Baragaña B, Wyllie S, Baum J, Baldwin GS, Weerapana E, Tate EW, Child MA. Benns HJ, et al. Nat Microbiol. 2022 Nov;7(11):1891-1905. doi: 10.1038/s41564-022-01249-y. Epub 2022 Oct 20. Nat Microbiol. 2022. PMID: 36266336 Free PMC article.
Reversible lysine-targeted probes reveal residence time-based kinase selectivity.
Yang T, Cuesta A, Wan X, Craven GB, Hirakawa B, Khamphavong P, May JR, Kath JC, Lapek JD Jr, Niessen S, Burlingame AL, Carelli JD, Taunton J. Yang T, et al. Among authors: craven gb. Nat Chem Biol. 2022 Sep;18(9):934-941. doi: 10.1038/s41589-022-01019-1. Epub 2022 May 19. Nat Chem Biol. 2022. PMID: 35590003 Free PMC article.
14 results