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Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY. Tobe BTD, et al. Among authors: crain am. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12. Proc Natl Acad Sci U S A. 2017. PMID: 28500272 Free PMC article.
Phosphoproteomic analysis of human embryonic stem cells.
Brill LM, Xiong W, Lee KB, Ficarro SB, Crain A, Xu Y, Terskikh A, Snyder EY, Ding S. Brill LM, et al. Cell Stem Cell. 2009 Aug 7;5(2):204-13. doi: 10.1016/j.stem.2009.06.002. Cell Stem Cell. 2009. PMID: 19664994 Free PMC article.
Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling.
Singec I, Crain AM, Hou J, Tobe BTD, Talantova M, Winquist AA, Doctor KS, Choy J, Huang X, La Monaca E, Horn DM, Wolf DA, Lipton SA, Gutierrez GJ, Brill LM, Snyder EY. Singec I, et al. Among authors: crain am. Stem Cell Reports. 2016 Sep 13;7(3):527-542. doi: 10.1016/j.stemcr.2016.07.019. Epub 2016 Aug 25. Stem Cell Reports. 2016. PMID: 27569059 Free PMC article.
Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.
Logan RW, Ozburn AR, Arey RN, Ketchesin KD, Winquist A, Crain A, Tobe BTD, Becker-Krail D, Jarpe MB, Xue X, Zong W, Huo Z, Parekh PK, Zhu X, Fitzgerald E, Zhang H, Oliver-Smith J, DePoy LM, Hildebrand MA, Snyder EY, Tseng GC, McClung CA. Logan RW, et al. Mol Psychiatry. 2021 Aug;26(8):4066-4084. doi: 10.1038/s41380-020-00958-2. Epub 2020 Nov 24. Mol Psychiatry. 2021. PMID: 33235333 Free PMC article.
The leading edge of stem cell therapeutics.
Singec I, Jandial R, Crain A, Nikkhah G, Snyder EY. Singec I, et al. Annu Rev Med. 2007;58:313-28. doi: 10.1146/annurev.med.58.070605.115252. Annu Rev Med. 2007. PMID: 17100553 Review.
Neural Stem Cells Derived from Human Parthenogenetic Stem Cells Engraft and Promote Recovery in a Nonhuman Primate Model of Parkinson's Disease.
Gonzalez R, Garitaonandia I, Poustovoitov M, Abramihina T, McEntire C, Culp B, Attwood J, Noskov A, Christiansen-Weber T, Khater M, Mora-Castilla S, To C, Crain A, Sherman G, Semechkin A, Laurent LC, Elsworth JD, Sladek J, Snyder EY, Redmond DE Jr, Kern RA. Gonzalez R, et al. Cell Transplant. 2016 Nov;25(11):1945-1966. doi: 10.3727/096368916X691682. Cell Transplant. 2016. PMID: 27213850 Free article.
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