Cracan V - Search Results

1

A genetically encoded tool to increase cellular NADH/NAD⁺ ratio in living cells.

Pan X, Heacock ML, Abdulaziz EN, Violante S, Zuckerman AL, Shrestha N, Yao C, Goodman RP, Cross JR, Cracan V. Pan X, et al. Among authors: cracan v. Nat Chem Biol. 2024 May;20(5):594-604. doi: 10.1038/s41589-023-01460-w. Epub 2023 Oct 26. Nat Chem Biol. 2024. PMID: 37884806 Free PMC article.

2

Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.

Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK. Titov DV, et al. Among authors: cracan v. Science. 2016 Apr 8;352(6282):231-5. doi: 10.1126/science.aad4017. Epub 2016 Apr 7. Science. 2016. PMID: 27124460 Free PMC article.

3

A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis.

Abdulaziz EN, Bell TA, Rashid B, Heacock ML, Begic T, Skinner OS, Yaseen MA, Chao LH, Mootha VK, Pierik AJ, Cracan V. Abdulaziz EN, et al. Among authors: cracan v. J Biol Chem. 2022 Aug;298(8):102210. doi: 10.1016/j.jbc.2022.102210. Epub 2022 Jun 30. J Biol Chem. 2022. PMID: 35780837 Free PMC article.

4

A genetically encoded tool for manipulation of NADP⁺/NADPH in living cells.

Cracan V, Titov DV, Shen H, Grabarek Z, Mootha VK. Cracan V, et al. Nat Chem Biol. 2017 Oct;13(10):1088-1095. doi: 10.1038/nchembio.2454. Epub 2017 Aug 7. Nat Chem Biol. 2017. PMID: 28805804 Free PMC article.

5

Downregulation of the tyrosine degradation pathway extends Drosophila lifespan.

Parkhitko AA, Ramesh D, Wang L, Leshchiner D, Filine E, Binari R, Olsen AL, Asara JM, Cracan V, Rabinowitz JD, Brockmann A, Perrimon N. Parkhitko AA, et al. Among authors: cracan v. Elife. 2020 Dec 15;9:e58053. doi: 10.7554/eLife.58053. Elife. 2020. PMID: 33319750 Free PMC article.

6

Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.

Gohil VM, Zhu L, Baker CD, Cracan V, Yaseen A, Jain M, Clish CB, Brookes PS, Bakovic M, Mootha VK. Gohil VM, et al. Among authors: cracan v. J Biol Chem. 2013 Dec 6;288(49):35387-95. doi: 10.1074/jbc.M113.489237. Epub 2013 Oct 19. J Biol Chem. 2013. PMID: 24142790 Free PMC article.

7

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.

Singh C, Jin B, Shrestha N, Markhard AL, Panda A, Calvo SE, Deik A, Pan X, Zuckerman AL, Ben Saad A, Corey KE, Sjoquist J, Osganian S, AminiTabrizi R, Rhee EP, Shah H, Goldberger O, Mullen AC, Cracan V, Clish CB, Mootha VK, Goodman RP. Singh C, et al. Among authors: cracan v. Cell Metab. 2024 Jan 2;36(1):144-158.e7. doi: 10.1016/j.cmet.2023.11.010. Epub 2023 Dec 14. Cell Metab. 2024. PMID: 38101397

8

Cofactor Editing by the G-protein Metallochaperone Domain Regulates the Radical B₁₂ Enzyme IcmF.

Li Z, Kitanishi K, Twahir UT, Cracan V, Chapman D, Warncke K, Banerjee R. Li Z, et al. Among authors: cracan v. J Biol Chem. 2017 Mar 10;292(10):3977-3987. doi: 10.1074/jbc.M117.775957. Epub 2017 Jan 27. J Biol Chem. 2017. PMID: 28130442 Free PMC article.

9

Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.

Jost M, Born DA, Cracan V, Banerjee R, Drennan CL. Jost M, et al. Among authors: cracan v. J Biol Chem. 2015 Nov 6;290(45):26882-26898. doi: 10.1074/jbc.M115.676890. Epub 2015 Aug 28. J Biol Chem. 2015. PMID: 26318610 Free PMC article.

10

Engineered and Native Coenzyme B12-dependent Isovaleryl-CoA/Pivalyl-CoA Mutase.

Kitanishi K, Cracan V, Banerjee R. Kitanishi K, et al. Among authors: cracan v. J Biol Chem. 2015 Aug 14;290(33):20466-76. doi: 10.1074/jbc.M115.646299. Epub 2015 Jul 1. J Biol Chem. 2015. PMID: 26134562 Free PMC article.

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