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An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis.
Gauthier C, Raynaud P, Jean-Alphonse F, Vallet A, Vaugrente O, Jugnarain V, Boulo T, Gauthier C, Reiter E, Bruneau G, Crépieux P. Gauthier C, et al. Among authors: crepieux p. Mol Cell Endocrinol. 2024 Apr 15;589:112235. doi: 10.1016/j.mce.2024.112235. Online ahead of print. Mol Cell Endocrinol. 2024. PMID: 38621656 Free article.
Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR.
Zehnaker A, Vallet A, Gourdon J, Sarti C, Jugnarain V, Haj Hassan M, Mathias L, Gauthier C, Raynaud P, Boulo T, Beauclair L, Bigot Y, Casarini L, Crépieux P, Poupon A, Piégu B, Jean-Alphonse F, Bruneau G, Reiter É. Zehnaker A, et al. Among authors: crepieux p. Int J Mol Sci. 2023 Nov 4;24(21):15961. doi: 10.3390/ijms242115961. Int J Mol Sci. 2023. PMID: 37958944 Free PMC article.
Intracellular VHHs to monitor and modulate GPCR signaling.
Raynaud P, Gauthier C, Jugnarain V, Jean-Alphonse F, Reiter E, Bruneau G, Crépieux P. Raynaud P, et al. Among authors: crepieux p. Front Endocrinol (Lausanne). 2022 Nov 16;13:1048601. doi: 10.3389/fendo.2022.1048601. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465650 Free PMC article. Review.
A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity.
Musnier A, Bourquard T, Vallet A, Mathias L, Bruneau G, Ayoub MA, Travert O, Corde Y, Gallay N, Boulo T, Cortes S, Watier H, Crépieux P, Reiter E, Poupon A. Musnier A, et al. Among authors: crepieux p. Int J Mol Sci. 2022 Aug 28;23(17):9765. doi: 10.3390/ijms23179765. Int J Mol Sci. 2022. PMID: 36077163 Free PMC article.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, Viaud-Massuard MC, Casarini L, Simoni M, Hanyaloglu AC, Nataraja SG, Yu HN, Palmer SS, Yvinec R, Reiter E. De Pascali F, et al. Among authors: crepieux p. Int J Mol Sci. 2021 Sep 12;22(18):9850. doi: 10.3390/ijms22189850. Int J Mol Sci. 2021. PMID: 34576014 Free PMC article.
Accurate determination of epitope for antibodies with unknown 3D structures.
Tahir S, Bourquard T, Musnier A, Jullian Y, Corde Y, Omahdi Z, Mathias L, Reiter E, Crépieux P, Bruneau G, Poupon A. Tahir S, et al. Among authors: crepieux p. MAbs. 2021 Jan-Dec;13(1):1961349. doi: 10.1080/19420862.2021.1961349. MAbs. 2021. PMID: 34432559 Free PMC article.
Reduced FSH and LH action: implications for medically assisted reproduction.
Bosch E, Alviggi C, Lispi M, Conforti A, Hanyaloglu AC, Chuderland D, Simoni M, Raine-Fenning N, Crépieux P, Kol S, Rochira V, D'Hooghe T, Humaidan P. Bosch E, et al. Among authors: crepieux p. Hum Reprod. 2021 May 17;36(6):1469-1480. doi: 10.1093/humrep/deab065. Hum Reprod. 2021. PMID: 33792685 Free PMC article. Review.
Direct impact of gonadotropins on glucose uptake and storage in preovulatory granulosa cells: Implications in the pathogenesis of polycystic ovary syndrome.
Chahal N, Geethadevi A, Kaur S, Lakra R, Nagendra A, Shrivastav TG, De Pascali F, Reiter E, Crépieux P, Devi MG, Malhotra N, Muralidhar K, Singh R. Chahal N, et al. Among authors: crepieux p. Metabolism. 2021 Feb;115:154458. doi: 10.1016/j.metabol.2020.154458. Epub 2020 Dec 2. Metabolism. 2021. PMID: 33278413
79 results