Cox CD - Search Results

1

Membrane curvature governs the distribution of Piezo1 in live cells.

Yang S, Miao X, Arnold S, Li B, Ly AT, Wang H, Wang M, Guo X, Pathak MM, Zhao W, Cox CD, Shi Z. Yang S, et al. Among authors: cox cd. Nat Commun. 2022 Dec 3;13(1):7467. doi: 10.1038/s41467-022-35034-6. Nat Commun. 2022. PMID: 36463216 Free PMC article.

2

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension.

Cox CD, Bae C, Ziegler L, Hartley S, Nikolova-Krstevski V, Rohde PR, Ng CA, Sachs F, Gottlieb PA, Martinac B. Cox CD, et al. Nat Commun. 2016 Jan 20;7:10366. doi: 10.1038/ncomms10366. Nat Commun. 2016. PMID: 26785635 Free PMC article.

3

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.

Bavi N, Cortes DM, Cox CD, Rohde PR, Liu W, Deitmer JW, Bavi O, Strop P, Hill AP, Rees D, Corry B, Perozo E, Martinac B. Bavi N, et al. Among authors: cox cd. Nat Commun. 2016 Jun 22;7:11984. doi: 10.1038/ncomms11984. Nat Commun. 2016. PMID: 27329693 Free PMC article.

4

Visualization of the mechanosensitive ion channel MscS under membrane tension.

Zhang Y, Daday C, Gu RX, Cox CD, Martinac B, de Groot BL, Walz T. Zhang Y, et al. Among authors: cox cd. Nature. 2021 Feb;590(7846):509-514. doi: 10.1038/s41586-021-03196-w. Epub 2021 Feb 10. Nature. 2021. PMID: 33568813

5

Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations.

Li JV, Ng CA, Cheng D, Zhou Z, Yao M, Guo Y, Yu ZY, Ramaswamy Y, Ju LA, Kuchel PW, Feneley MP, Fatkin D, Cox CD. Li JV, et al. Among authors: cox cd. Commun Biol. 2021 Sep 6;4(1):1038. doi: 10.1038/s42003-021-02528-w. Commun Biol. 2021. PMID: 34489534 Free PMC article.

6

Author Correction: Membrane curvature governs the distribution of Piezo1 in live cells.

Yang S, Miao X, Arnold S, Li B, Ly AT, Wang H, Wang M, Guo X, Pathak MM, Zhao W, Cox CD, Shi Z. Yang S, et al. Among authors: cox cd. Nat Commun. 2023 Jan 31;14(1):524. doi: 10.1038/s41467-023-36108-9. Nat Commun. 2023. PMID: 36720871 Free PMC article. No abstract available.

7

A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.

Zhang M, Shan Y, Cox CD, Pei D. Zhang M, et al. Among authors: cox cd. Nat Commun. 2023 Jul 4;14(1):3943. doi: 10.1038/s41467-023-39688-8. Nat Commun. 2023. PMID: 37402734 Free PMC article.

8

Mechanical activation opens a lipid-lined pore in OSCA ion channels.

Han Y, Zhou Z, Jin R, Dai F, Ge Y, Ju X, Ma X, He S, Yuan L, Wang Y, Yang W, Yue X, Chen Z, Sun Y, Corry B, Cox CD, Zhang Y. Han Y, et al. Among authors: cox cd. Nature. 2024 Apr;628(8009):910-918. doi: 10.1038/s41586-024-07256-9. Epub 2024 Apr 3. Nature. 2024. PMID: 38570680

9

Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters.

Ridone P, Pandzic E, Vassalli M, Cox CD, Macmillan A, Gottlieb PA, Martinac B. Ridone P, et al. Among authors: cox cd. J Gen Physiol. 2020 Aug 3;152(8):e201912515. doi: 10.1085/jgp.201912515. J Gen Physiol. 2020. PMID: 32582958 Free PMC article.

10

Loss-of-Function Piezo1 Mutations Display Altered Stability Driven by Ubiquitination and Proteasomal Degradation.

Zhou Z, Li JV, Martinac B, Cox CD. Zhou Z, et al. Among authors: cox cd. Front Pharmacol. 2021 Nov 19;12:766416. doi: 10.3389/fphar.2021.766416. eCollection 2021. Front Pharmacol. 2021. PMID: 34867393 Free PMC article.

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