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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: covey df. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling.
Kinnebrew M, Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R. Kinnebrew M, et al. Among authors: covey df. Elife. 2019 Oct 30;8:e50051. doi: 10.7554/eLife.50051. Elife. 2019. PMID: 31657721 Free PMC article.
Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages.
Li Y, Ge M, Ciani L, Kuriakose G, Westover EJ, Dura M, Covey DF, Freed JH, Maxfield FR, Lytton J, Tabas I. Li Y, et al. Among authors: covey df. J Biol Chem. 2004 Aug 27;279(35):37030-9. doi: 10.1074/jbc.M405195200. Epub 2004 Jun 23. J Biol Chem. 2004. PMID: 15215242 Free article.
The enantiomer of cholesterol.
Westover EJ, Covey DF. Westover EJ, et al. Among authors: covey df. J Membr Biol. 2004 Nov;202(2):61-72. doi: 10.1007/s00232-004-0714-7. J Membr Biol. 2004. PMID: 15702370 Review.
Oxysterols as non-genomic regulators of cholesterol homeostasis.
Bielska AA, Schlesinger P, Covey DF, Ory DS. Bielska AA, et al. Among authors: covey df. Trends Endocrinol Metab. 2012 Mar;23(3):99-106. doi: 10.1016/j.tem.2011.12.002. Epub 2012 Jan 11. Trends Endocrinol Metab. 2012. PMID: 22244444 Free PMC article.
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Kinnebrew M, Woolley RE, Ansell TB, Byrne EFX, Frigui S, Luchetti G, Sircar R, Nachtergaele S, Mydock-McGrane L, Krishnan K, Newstead S, Sansom MSP, Covey DF, Siebold C, Rohatgi R. Kinnebrew M, et al. Among authors: covey df. Sci Adv. 2022 Jun 3;8(22):eabm5563. doi: 10.1126/sciadv.abm5563. Epub 2022 Jun 3. Sci Adv. 2022. PMID: 35658032 Free PMC article.
Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling.
Cheng WWL, Budelier MM, Sugasawa Y, Bergdoll L, Queralt-Martín M, Rosencrans W, Rostovtseva TK, Chen ZW, Abramson J, Krishnan K, Covey DF, Whitelegge JP, Evers AS. Cheng WWL, et al. Among authors: covey df. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1269-1279. doi: 10.1016/j.bbalip.2019.06.004. Epub 2019 Jun 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31176038 Free PMC article.
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. Shin HR, et al. Among authors: covey df. Science. 2022 Sep 16;377(6612):1290-1298. doi: 10.1126/science.abg6621. Epub 2022 Aug 25. Science. 2022. PMID: 36007018 Free PMC article.
334 results