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Alcohols inhibit a cloned potassium channel at a discrete saturable site. Insights into the molecular basis of general anesthesia.
Covarrubias M, Vyas TB, Escobar L, Wei A. Covarrubias M, et al. J Biol Chem. 1995 Aug 18;270(33):19408-16. doi: 10.1074/jbc.270.33.19408. J Biol Chem. 1995. PMID: 7642622 Free article.
The molecular basis of general anesthetic action on membrane proteins that control ion transport is not yet understood. In a previous report (Covarrubias, M., and Rubin, E. (1993) Proc. Natl. Acad. Sci. 90, 6957-6960), we found that low concentrations of ethanol (17 …
The molecular basis of general anesthetic action on membrane proteins that control ion transport is not yet understood. In a previous report …
Inactivation gating of Kv4 potassium channels: molecular interactions involving the inner vestibule of the pore.
Jerng HH, Shahidullah M, Covarrubias M. Jerng HH, et al. Among authors: covarrubias m. J Gen Physiol. 1999 May;113(5):641-60. doi: 10.1085/jgp.113.5.641. J Gen Physiol. 1999. PMID: 10228180 Free PMC article.
A previous study suggested that the cytoplasmic NH2- and COOH-terminal domains of Kv4.1 channels act in concert to determine the fast phase of the complex time course of macroscopic inactivation (Jerng, H.H., and M. Covarrubias. 1997. Biophys. J. 72:163-174). To inv …
A previous study suggested that the cytoplasmic NH2- and COOH-terminal domains of Kv4.1 channels act in concert to determine the fast phase …
134 results