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The dose threshold for nanoparticle tumour delivery.
Nat Mater. 2020 Dec;19(12):1362-1371. doi: 10.1038/s41563-020-0755-z. Epub 2020 Aug 10.
Nat Mater. 2020.
PMID: 32778816
Impact of Tumor Barriers on Nanoparticle Delivery to Macrophages.
Ouyang B, Kingston BR, Poon W, Zhang YN, Lin ZP, Syed AM, Couture-Senécal J, Chan WCW.
Ouyang B, et al. Among authors: couture senecal j.
Mol Pharm. 2022 Jun 6;19(6):1917-1925. doi: 10.1021/acs.molpharmaceut.1c00905. Epub 2022 Mar 23.
Mol Pharm. 2022.
PMID: 35319220
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Ionizable Lipid with Supramolecular Chemistry Features for RNA Delivery In Vivo.
Manning AM, Tilstra G, Khan AB, Couture-Senécal J, Lau YMA, Pang J, Abow AA, Robbins CS, Khan OF.
Manning AM, et al. Among authors: couture senecal j.
Small. 2023 Oct;19(41):e2302917. doi: 10.1002/smll.202302917. Epub 2023 Jun 13.
Small. 2023.
PMID: 37312676
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Iterative Design of Ionizable Lipids for Intramuscular mRNA Delivery.
Tilstra G, Couture-Senécal J, Lau YMA, Manning AM, Wong DSM, Janaeska WW, Wuraola TA, Pang J, Khan OF.
Tilstra G, et al. Among authors: couture senecal j.
J Am Chem Soc. 2023 Feb 1;145(4):2294-2304. doi: 10.1021/jacs.2c10670. Epub 2023 Jan 18.
J Am Chem Soc. 2023.
PMID: 36652629
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The engineering challenges and opportunities when designing potent ionizable materials for the delivery of ribonucleic acids.
Lau YMA, Pang J, Tilstra G, Couture-Senécal J, Khan OF.
Lau YMA, et al. Among authors: couture senecal j.
Expert Opin Drug Deliv. 2022 Dec;19(12):1650-1663. doi: 10.1080/17425247.2022.2144827. Epub 2022 Nov 21.
Expert Opin Drug Deliv. 2022.
PMID: 36377494
Review.
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