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The dose threshold for nanoparticle tumour delivery.
Ouyang B, Poon W, Zhang YN, Lin ZP, Kingston BR, Tavares AJ, Zhang Y, Chen J, Valic MS, Syed AM, MacMillan P, Couture-Senécal J, Zheng G, Chan WCW. Ouyang B, et al. Among authors: couture senecal j. Nat Mater. 2020 Dec;19(12):1362-1371. doi: 10.1038/s41563-020-0755-z. Epub 2020 Aug 10. Nat Mater. 2020. PMID: 32778816
Impact of Tumor Barriers on Nanoparticle Delivery to Macrophages.
Ouyang B, Kingston BR, Poon W, Zhang YN, Lin ZP, Syed AM, Couture-Senécal J, Chan WCW. Ouyang B, et al. Among authors: couture senecal j. Mol Pharm. 2022 Jun 6;19(6):1917-1925. doi: 10.1021/acs.molpharmaceut.1c00905. Epub 2022 Mar 23. Mol Pharm. 2022. PMID: 35319220
Iterative Design of Ionizable Lipids for Intramuscular mRNA Delivery.
Tilstra G, Couture-Senécal J, Lau YMA, Manning AM, Wong DSM, Janaeska WW, Wuraola TA, Pang J, Khan OF. Tilstra G, et al. Among authors: couture senecal j. J Am Chem Soc. 2023 Feb 1;145(4):2294-2304. doi: 10.1021/jacs.2c10670. Epub 2023 Jan 18. J Am Chem Soc. 2023. PMID: 36652629