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Empagliflozin reduces arrhythmogenic effects in rat neonatal and human iPSC-derived cardiomyocytes and improves cytosolic calcium handling at least partially independent of NHE1.
Silva Dos Santos D, Turaça LT, Coutinho KCDS, Barbosa RAQ, Polidoro JZ, Kasai-Brunswick TH, Campos de Carvalho AC, Girardi ACC. Silva Dos Santos D, et al. Among authors: coutinho kcds. Sci Rep. 2023 May 29;13(1):8689. doi: 10.1038/s41598-023-35944-5. Sci Rep. 2023. PMID: 37248416 Free PMC article.
Action potential variability in human pluripotent stem cell-derived cardiomyocytes obtained from healthy donors.
Carvalho AB, Coutinho KCDS, Barbosa RAQ, de Campos DBP, Leitão IC, Pinto RS, Dos Santos DS, Farjun B, De Araújo DDS, Mesquita FCP, Monnerat-Cahli G, Medei EH, Kasai-Brunswick TH, De Carvalho ACC. Carvalho AB, et al. Among authors: coutinho kcds. Front Physiol. 2022 Dec 16;13:1077069. doi: 10.3389/fphys.2022.1077069. eCollection 2022. Front Physiol. 2022. PMID: 36589430 Free PMC article.