Couly S - Search Results

1

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models.

Crouzier L, Danese A, Yasui Y, Richard EM, Liévens JC, Patergnani S, Couly S, Diez C, Denus M, Cubedo N, Rossel M, Thiry M, Su TP, Pinton P, Maurice T, Delprat B. Crouzier L, et al. Among authors: couly s. Sci Transl Med. 2022 Feb 9;14(631):eabh3763. doi: 10.1126/scitranslmed.abh3763. Epub 2022 Feb 9. Sci Transl Med. 2022. PMID: 35138910 Free PMC article.

2

Improvement of BDNF signalling by P42 peptide in Huntington's disease.

Couly S, Paucard A, Bonneaud N, Maurice T, Benigno L, Jourdan C, Cohen-Solal C, Vignes M, Maschat F. Couly S, et al. Hum Mol Genet. 2018 Sep 1;27(17):3012-3028. doi: 10.1093/hmg/ddy207. Hum Mol Genet. 2018. PMID: 29860423

3

Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis.

Couly S, Khalil B, Viguier V, Roussel J, Maurice T, Liévens JC. Couly S, et al. Hum Mol Genet. 2020 Mar 13;29(4):529-540. doi: 10.1093/hmg/ddz267. Hum Mol Genet. 2020. PMID: 31696229

4

Sigma-1 (σ₁) receptor activity is necessary for physiological brain plasticity in mice.

Crouzier L, Couly S, Roques C, Peter C, Belkhiter R, Arguel Jacquemin M, Bonetto A, Delprat B, Maurice T. Crouzier L, et al. Among authors: couly s. Eur Neuropsychopharmacol. 2020 Oct;39:29-45. doi: 10.1016/j.euroneuro.2020.08.010. Epub 2020 Sep 3. Eur Neuropsychopharmacol. 2020. PMID: 32893057

5

Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer's Disease.

Couly S, Denus M, Bouchet M, Rubinstenn G, Maurice T. Couly S, et al. Int J Neuropsychopharmacol. 2021 Feb 15;24(2):142-157. doi: 10.1093/ijnp/pyaa075. Int J Neuropsychopharmacol. 2021. PMID: 32977336 Free PMC article.

6

Knocking Out Sigma-1 Receptors Reveals Diverse Health Problems.

Couly S, Goguadze N, Yasui Y, Kimura Y, Wang SM, Sharikadze N, Wu HE, Su TP. Couly S, et al. Cell Mol Neurobiol. 2022 Apr;42(3):597-620. doi: 10.1007/s10571-020-00983-3. Epub 2020 Oct 23. Cell Mol Neurobiol. 2022. PMID: 33095392 Free PMC article. Review.

7

Exposure of R6/2 mice in an enriched environment augments P42 therapy efficacy on Huntington's disease progression.

Couly S, Carles A, Denus M, Benigno-Anton L, Maschat F, Maurice T. Couly S, et al. Neuropharmacology. 2021 Mar 15;186:108467. doi: 10.1016/j.neuropharm.2021.108467. Epub 2021 Jan 28. Neuropharmacology. 2021. PMID: 33516737

8

SIGMAR1 Confers Innate Resilience against Neurodegeneration.

Couly S, Yasui Y, Su TP. Couly S, et al. Int J Mol Sci. 2023 Apr 24;24(9):7767. doi: 10.3390/ijms24097767. Int J Mol Sci. 2023. PMID: 37175473 Free PMC article. Review.

9

Benzomorphan and non-benzomorphan agonists differentially alter sigma-1 receptor quaternary structure, as does types of cellular stress.

Couly S, Yasui Y, Foncham S, Grammatikakis I, Lal A, Shi L, Su TP. Couly S, et al. Cell Mol Life Sci. 2024 Jan 9;81(1):14. doi: 10.1007/s00018-023-05023-z. Cell Mol Life Sci. 2024. PMID: 38191696 Free PMC article.

10

Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice.

Pagnamenta AT, Heemeryck P, Martin HC, Bosc C, Peris L, Uszynski I, Gory-Fauré S, Couly S, Deshpande C, Siddiqui A, Elmonairy AA; WGS500 Consortium; Genomics England Research Consortium; Jayawant S, Murthy S, Walker I, Loong L, Bauer P, Vossier F, Denarier E, Maurice T, Barbier EL, Deloulme JC, Taylor JC, Blair EM, Andrieux A, Moutin MJ. Pagnamenta AT, et al. Among authors: couly s. Hum Mol Genet. 2019 Oct 15;28(20):3391-3405. doi: 10.1093/hmg/ddz186. Hum Mol Genet. 2019. PMID: 31363758 Free PMC article.

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