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ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.
O'Sullivan J, Kothari C, Caron MC, Gagné JP, Jin Z, Nonfoux L, Beneyton A, Coulombe Y, Thomas M, Atalay N, Meng XW, Milano L, Jean D, Boisvert FM, Kaufmann SH, Hendzel MJ, Masson JY, Poirier GG. O'Sullivan J, et al. Among authors: coulombe y. Nucleic Acids Res. 2023 Nov 10;51(20):11056-11079. doi: 10.1093/nar/gkad791. Nucleic Acids Res. 2023. PMID: 37823600 Free PMC article.
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.
Dubois EL, Guitton-Sert L, Béliveau M, Parmar K, Chagraoui J, Vignard J, Pauty J, Caron MC, Coulombe Y, Buisson R, Jacquet K, Gamblin C, Gao Y, Laprise P, Lebel M, Sauvageau G, D d'Andrea A, Masson JY. Dubois EL, et al. Among authors: coulombe y. Nucleic Acids Res. 2019 Aug 22;47(14):7532-7547. doi: 10.1093/nar/gkz514. Nucleic Acids Res. 2019. PMID: 31219578 Free PMC article.
Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks.
Caron MC, Sharma AK, O'Sullivan J, Myler LR, Ferreira MT, Rodrigue A, Coulombe Y, Ethier C, Gagné JP, Langelier MF, Pascal JM, Finkelstein IJ, Hendzel MJ, Poirier GG, Masson JY. Caron MC, et al. Among authors: coulombe y. Nat Commun. 2019 Jul 4;10(1):2954. doi: 10.1038/s41467-019-10741-9. Nat Commun. 2019. PMID: 31273204 Free PMC article.
Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction.
Couturier AM, Fleury H, Patenaude AM, Bentley VL, Rodrigue A, Coulombe Y, Niraj J, Pauty J, Berman JN, Dellaire G, Di Noia JM, Mes-Masson AM, Masson JY. Couturier AM, et al. Among authors: coulombe y. Nucleic Acids Res. 2016 Dec 15;44(22):10879-10897. doi: 10.1093/nar/gkw921. Epub 2016 Oct 24. Nucleic Acids Res. 2016. PMID: 27924011 Free PMC article.
38 results