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WT1 gene is overexpressed in myeloproliferative neoplasms, especially in myelofibrosis.
Cottin L, Riou J, Boyer F, Bouvier A, Zannetti A, Blouet A, Truchan-Graczyk M, Jouanneau-Courville R, Beucher A, Ribourtout B, Orvain C, Hunault-Berger M, Blanchet O, Ugo V, Luque Paz D. Cottin L, et al. Blood Cells Mol Dis. 2019 Mar;75:35-40. doi: 10.1016/j.bcmd.2018.12.004. Epub 2018 Dec 20. Blood Cells Mol Dis. 2019. PMID: 30612065 Free article.
Next generation sequencing redefines a triple negative essential thrombocythaemia as double-positive with rare mutations on JAK2 V617 and MPL W515 hotspots.
Beucher A, Dib M, Orvain C, Bouvier A, Jouanneau-Courville R, Dobo I, Cottin L, Guardiola P, Rousselet MC, Blanchet O, Hunault M, Ugo V, Luque Paz D. Beucher A, et al. Among authors: cottin l. Br J Haematol. 2019 Sep;186(5):785-788. doi: 10.1111/bjh.15954. Epub 2019 May 14. Br J Haematol. 2019. PMID: 31087331 Free article. No abstract available.
Quantitative chimerism in CD3-negative mononuclear cells predicts prognosis in acute myeloid leukemia patients after hematopoietic stem cell transplantation.
Bouvier A, Riou J, Thépot S, Sutra Del Galy A, François S, Schmidt A, Orvain C, Estienne MH, Villate A, Luque Paz D, Cottin L, Ribourtout B, Beucher A, Delneste Y, Ifrah N, Ugo V, Hunault-Berger M, Blanchet O. Bouvier A, et al. Among authors: cottin l. Leukemia. 2020 May;34(5):1342-1353. doi: 10.1038/s41375-019-0624-4. Epub 2019 Nov 25. Leukemia. 2020. PMID: 31768015
Different number of circulating CD34 + cells in essential thrombocythemia, prefibrotic/early primary myelofibrosis, and overt primary myelofibrosis.
Luque Paz D, Cottin L, Lippert E, Robin JB, Bescond C, Genevieve F, Boyer F, Quintin-Roue I, Rousselet MC, Burroni B, Hunault-Berger M, Ugo V, Ianotto JC, Orvain C. Luque Paz D, et al. Among authors: cottin l. Ann Hematol. 2022 Apr;101(4):893-896. doi: 10.1007/s00277-021-04672-z. Epub 2021 Oct 5. Ann Hematol. 2022. PMID: 34611719 No abstract available.
Circulating Cd34+ cell count differentiates primary myelofibrosis from other Philadelphia-negative myeloproliferative neoplasms: a pragmatic study.
Orvain C, Luque Paz D, Dobo I, Cottin L, Le Calvez G, Chauveau A, Mercier M, Farhi J, Boyer F, Ianotto JC, Guibourg B, Rousselet MC, Zandecki M, Ifrah N, Hunault-Berger M, Ugo V, Genevieve F. Orvain C, et al. Among authors: cottin l. Ann Hematol. 2016 Oct;95(11):1819-23. doi: 10.1007/s00277-016-2784-x. Epub 2016 Sep 1. Ann Hematol. 2016. PMID: 27582015
Sequential mutational evaluation of CALR -mutated myeloproliferative neoplasms with thrombocytosis reveals an association between CALR allele burden evolution and disease progression.
Cottin L, Riou J, Orvain C, Ianotto JC, Boyer F, Renard M, Truchan-Graczyk M, Murati A, Jouanneau-Courville R, Allangba O, Mansier O, Burroni B, Rousselet MC, Quintin-Roué I, Martin A, Sadot-Lebouvier S, Delneste Y, Chrétien JM, Hunault-Berger M, Blanchet O, Lippert E, Ugo V, Luque Paz D. Cottin L, et al. Br J Haematol. 2020 Mar;188(6):935-944. doi: 10.1111/bjh.16276. Epub 2019 Nov 11. Br J Haematol. 2020. PMID: 31710700 Free article.
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