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Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, Thompson LM, Steffan JS, Smith I, Davtyan H, Cahalan M, Cho H, Blurton-Jones M. McQuade A, et al. Among authors: cotman c. Nat Commun. 2020 Oct 23;11(1):5370. doi: 10.1038/s41467-020-19227-5. Nat Commun. 2020. PMID: 33097708 Free PMC article.
β-Amyloid impairs axonal BDNF retrograde trafficking.
Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. Poon WW, et al. Neurobiol Aging. 2011 May;32(5):821-33. doi: 10.1016/j.neurobiolaging.2009.05.012. Epub 2009 Jun 21. Neurobiol Aging. 2011. PMID: 19540623 Free PMC article.
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M. Rodriguez-Ortiz CJ, et al. Among authors: cotman cw. Aging Cell. 2020 Mar;19(3):e13118. doi: 10.1111/acel.13118. Epub 2020 Feb 22. Aging Cell. 2020. PMID: 32087004 Free PMC article.
734 results