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Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease.
Garrido-Maraver J, Cordero MD, Moñino ID, Pereira-Arenas S, Lechuga-Vieco AV, Cotán D, De la Mata M, Oropesa-Ávila M, De Miguel M, Bautista Lorite J, Rivas Infante E, Alvarez-Dolado M, Navas P, Jackson S, Francisci S, Sánchez-Alcázar JA. Garrido-Maraver J, et al. Among authors: cotan d. Br J Pharmacol. 2012 Nov;167(6):1311-28. doi: 10.1111/j.1476-5381.2012.02086.x. Br J Pharmacol. 2012. PMID: 22747838 Free PMC article.
Recovery of MERRF fibroblasts and cybrids pathophysiology by coenzyme Q10.
De la Mata M, Garrido-Maraver J, Cotán D, Cordero MD, Oropesa-Ávila M, Izquierdo LG, De Miguel M, Lorite JB, Infante ER, Ybot P, Jackson S, Sánchez-Alcázar JA. De la Mata M, et al. Among authors: cotan d. Neurotherapeutics. 2012 Apr;9(2):446-63. doi: 10.1007/s13311-012-0103-3. Neurotherapeutics. 2012. PMID: 22354625 Free PMC article.
Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease.
de la Mata M, Cotán D, Oropesa-Ávila M, Garrido-Maraver J, Cordero MD, Villanueva Paz M, Delgado Pavón A, Alcocer-Gómez E, de Lavera I, Ybot-González P, Paula Zaderenko A, Ortiz Mellet C, García Fernández JM, Sánchez-Alcázar JA. de la Mata M, et al. Among authors: cotan d. Sci Rep. 2015 Jun 5;5:10903. doi: 10.1038/srep10903. Sci Rep. 2015. PMID: 26045184 Free PMC article.
Stabilization of apoptotic cells: generation of zombie cells.
Oropesa-Ávila M, Andrade-Talavera Y, Garrido-Maraver J, Cordero MD, de la Mata M, Cotán D, Paz MV, Pavón AD, Alcocer-Gómez E, de Lavera I, Lema R, Zaderenko AP, Rodríguez-Moreno A, Sánchez-Alcázar JA. Oropesa-Ávila M, et al. Among authors: cotan d. Cell Death Dis. 2014 Aug 14;5(8):e1369. doi: 10.1038/cddis.2014.332. Cell Death Dis. 2014. PMID: 25118929 Free PMC article.
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy.
Rodríguez-Hernández A, Cordero MD, Salviati L, Artuch R, Pineda M, Briones P, Gómez Izquierdo L, Cotán D, Navas P, Sánchez-Alcázar JA. Rodríguez-Hernández A, et al. Among authors: cotan d. Autophagy. 2009 Jan;5(1):19-32. doi: 10.4161/auto.5.1.7174. Autophagy. 2009. PMID: 19115482 Free article.
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease.
Cordero MD, De Miguel M, Moreno Fernández AM, Carmona López IM, Garrido Maraver J, Cotán D, Gómez Izquierdo L, Bonal P, Campa F, Bullon P, Navas P, Sánchez Alcázar JA. Cordero MD, et al. Among authors: cotan d. Arthritis Res Ther. 2010;12(1):R17. doi: 10.1186/ar2918. Epub 2010 Jan 28. Arthritis Res Ther. 2010. PMID: 20109177 Free PMC article.
Clinical applications of coenzyme Q10.
Garrido-Maraver J, Cordero MD, Oropesa-Avila M, Vega AF, de la Mata M, Pavon AD, Alcocer-Gomez E, Calero CP, Paz MV, Alanis M, de Lavera I, Cotan D, Sanchez-Alcazar JA. Garrido-Maraver J, et al. Among authors: cotan d. Front Biosci (Landmark Ed). 2014 Jan 1;19(4):619-33. doi: 10.2741/4231. Front Biosci (Landmark Ed). 2014. PMID: 24389208 Free article. Review.
Coenzyme q10 therapy.
Garrido-Maraver J, Cordero MD, Oropesa-Ávila M, Fernández Vega A, de la Mata M, Delgado Pavón A, de Miguel M, Pérez Calero C, Villanueva Paz M, Cotán D, Sánchez-Alcázar JA. Garrido-Maraver J, et al. Among authors: cotan d. Mol Syndromol. 2014 Jul;5(3-4):187-97. doi: 10.1159/000360101. Mol Syndromol. 2014. PMID: 25126052 Free PMC article.
41 results