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Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Di Pisa F, Landi G, Dello Iacono L, Pozzi C, Borsari C, Ferrari S, Santucci M, Santarem N, Cordeiro-da-Silva A, Moraes CB, Alcantara LM, Fontana V, Freitas-Junior LH, Gul S, Kuzikov M, Behrens B, Pöhner I, Wade RC, Costi MP, Mangani S. Di Pisa F, et al. Among authors: costi mp. Molecules. 2017 Mar 8;22(3):426. doi: 10.3390/molecules22030426. Molecules. 2017. PMID: 28282886 Free PMC article.
Update on antifolate drugs targets.
Costi MP, Ferrari S. Costi MP, et al. Curr Drug Targets. 2001 Jun;2(2):135-66. doi: 10.2174/1389450013348669. Curr Drug Targets. 2001. PMID: 11469716 Review.
Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: evaluation of in vitro anti-cancer and anti-folate activities.
Corona P, Loriga M, Costi MP, Ferrari S, Paglietti G. Corona P, et al. Among authors: costi mp. Eur J Med Chem. 2008 Jan;43(1):189-203. doi: 10.1016/j.ejmech.2007.03.035. Epub 2007 Apr 18. Eur J Med Chem. 2008. PMID: 17532099
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development.
Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP. Cavazzuti A, et al. Among authors: costi mp. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. doi: 10.1073/pnas.0704384105. Epub 2008 Feb 1. Proc Natl Acad Sci U S A. 2008. PMID: 18245389 Free PMC article.
137 results