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Modulation of Biliary Cancer Chemo-Resistance Through MicroRNA-Mediated Rewiring of the Expansion of CD133+ Cells.
Carotenuto P, Hedayat S, Fassan M, Cardinale V, Lampis A, Guzzardo V, Vicentini C, Scarpa A, Cascione L, Costantini D, Carpino G, Alvaro D, Ghidini M, Trevisani F, Te Poele R, Salati M, Ventura S, Vlachogiannis G, Hahne JC, Boulter L, Forbes SJ, Guest RV, Cillo U, Said-Huntingford I, Begum R, Smyth E, Michalarea V, Cunningham D, Rimassa L, Santoro A, Roncalli M, Kirkin V, Clarke P, Workman P, Valeri N, Braconi C. Carotenuto P, et al. Among authors: costantini d. Hepatology. 2020 Sep;72(3):982-996. doi: 10.1002/hep.31094. Epub 2020 Sep 10. Hepatology. 2020. PMID: 31879968 Free PMC article.
DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma.
Nevi L, Di Matteo S, Carpino G, Zizzari IG, Samira S, Ambrosino V, Costantini D, Overi D, Giancotti A, Monti M, Bosco D, De Peppo V, Oddi A, De Rose AM, Melandro F, Bragazzi MC, Faccioli J, Massironi S, Grazi GL, Panici PB, Berloco PB, Giuliante F, Cardinale V, Invernizzi P, Caretti G, Gaudio E, Alvaro D. Nevi L, et al. Among authors: costantini d. Hepatology. 2021 Jan;73(1):144-159. doi: 10.1002/hep.31571. Hepatology. 2021. PMID: 32978808 Free PMC article.
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma.
Di Matteo S, Nevi L, Costantini D, Overi D, Carpino G, Safarikia S, Giulitti F, Napoletano C, Manzi E, De Rose AM, Melandro F, Bragazzi M, Berloco PB, Giuliante F, Grazi G, Giorgi A, Cardinale V, Adorini L, Gaudio E, Alvaro D. Di Matteo S, et al. Among authors: costantini d. PLoS One. 2019 Jan 24;14(1):e0210077. doi: 10.1371/journal.pone.0210077. eCollection 2019. PLoS One. 2019. PMID: 30677052 Free PMC article.
Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures.
Fraveto A, Cardinale V, Bragazzi MC, Giuliante F, De Rose AM, Grazi GL, Napoletano C, Semeraro R, Lustri AM, Costantini D, Nevi L, Di Matteo S, Renzi A, Carpino G, Gaudio E, Alvaro D. Fraveto A, et al. Among authors: costantini d. PLoS One. 2015 Nov 16;10(11):e0142124. doi: 10.1371/journal.pone.0142124. eCollection 2015. PLoS One. 2015. PMID: 26571380 Free PMC article.
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential.
Cardinale V, Carpino G, Overi D, Safarikia S, Zhang W, Kanke M, Franchitto A, Costantini D, Riccioni O, Nevi L, Chiappetta M, Onori P, Franchitto M, Bini S, Hung YH, Lai Q, Zizzari I, Nuti M, Nicoletti C, Checquolo S, Di Magno L, Giuli MV, Rossi M, Sethupathy P, Reid LM, Alvaro D, Gaudio E. Cardinale V, et al. Among authors: costantini d. J Hepatol. 2023 Jan;78(1):165-179. doi: 10.1016/j.jhep.2022.08.037. Epub 2022 Sep 9. J Hepatol. 2023. PMID: 36089156
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells.
Costantini D, Overi D, Casadei L, Cardinale V, Nevi L, Carpino G, Di Matteo S, Safarikia S, Valerio M, Melandro F, Bizzarri M, Manetti C, Berloco PB, Gaudio E, Alvaro D. Costantini D, et al. Sci Rep. 2019 Apr 3;9(1):5559. doi: 10.1038/s41598-019-41908-5. Sci Rep. 2019. PMID: 30944365 Free PMC article.
TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.
Lustri AM, Di Matteo S, Fraveto A, Costantini D, Cantafora A, Napoletano C, Bragazzi MC, Giuliante F, De Rose AM, Berloco PB, Grazi GL, Carpino G, Alvaro D. Lustri AM, et al. Among authors: costantini d. PLoS One. 2017 Sep 5;12(9):e0183932. doi: 10.1371/journal.pone.0183932. eCollection 2017. PLoS One. 2017. PMID: 28873435 Free PMC article.
233 results