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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Nat Commun. 2023 May 15;14(1):2779. doi: 10.1038/s41467-023-38410-y.
Nat Commun. 2023.
PMID: 37188705
Free PMC article.
The sirtuin family in cancer.
Costa-Machado LF, Fernandez-Marcos PJ.
Costa-Machado LF, et al.
Cell Cycle. 2019 Sep;18(18):2164-2196. doi: 10.1080/15384101.2019.1634953. Epub 2019 Jul 25.
Cell Cycle. 2019.
PMID: 31251117
Free PMC article.
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Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin.
Sierra-Ramirez A, López-Aceituno JL, Costa-Machado LF, Plaza A, Barradas M, Fernandez-Marcos PJ.
Sierra-Ramirez A, et al. Among authors: costa machado lf.
Aging (Albany NY). 2020 Jun 25;12(12):11337-11348. doi: 10.18632/aging.103607. Epub 2020 Jun 25.
Aging (Albany NY). 2020.
PMID: 32584785
Free PMC article.
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Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity.
Barradas M, Plaza A, Colmenarejo G, Lázaro I, Costa-Machado LF, Martín-Hernández R, Micó V, López-Aceituno JL, Herranz J, Pantoja C, Tejero H, Diaz-Ruiz A, Al-Shahrour F, Daimiel L, Loria-Kohen V, Ramirez de Molina A, Efeyan A, Serrano M, Pozo OJ, Sala-Vila A, Fernandez-Marcos PJ.
Barradas M, et al. Among authors: costa machado lf.
Nat Commun. 2022 Sep 27;13(1):5677. doi: 10.1038/s41467-022-33352-3.
Nat Commun. 2022.
PMID: 36167809
Free PMC article.
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Sirt1 protects from K-Ras-driven lung carcinogenesis.
Costa-Machado LF, Martín-Hernández R, Sanchez-Luengo MÁ, Hess K, Vales-Villamarin C, Barradas M, Lynch C, de la Nava D, Diaz-Ruiz A, de Cabo R, Cañamero M, Martinez L, Sanchez-Carbayo M, Herranz D, Serrano M, Fernandez-Marcos PJ.
Costa-Machado LF, et al.
EMBO Rep. 2018 Sep;19(9):e43879. doi: 10.15252/embr.201643879. Epub 2018 Jul 18.
EMBO Rep. 2018.
PMID: 30021836
Free PMC article.
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LXR stimulates a metabolic switch and reveals cholesterol homeostasis as a statin target in Tasmanian devil facial tumor disease.
Ikonomopoulou MP, Lopez-Mancheño Y, Novelle MG, Martinez-Uña M, Gangoda L, Pal M, Costa-Machado LF, Fernandez-Marcos PJ, Ramm GA, Fernandez-Rojo MA.
Ikonomopoulou MP, et al. Among authors: costa machado lf.
Cell Rep. 2021 Mar 16;34(11):108851. doi: 10.1016/j.celrep.2021.108851.
Cell Rep. 2021.
PMID: 33730574
Free article.
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