Costa-Lotufo LV - Search Results

1

Reversine exhibits antineoplastic activity in JAK2^V617F-positive myeloproliferative neoplasms.

Lima K, Carlos JAEG, Alves-Paiva RM, Vicari HP, Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Lima K, et al. Sci Rep. 2019 Jul 9;9(1):9895. doi: 10.1038/s41598-019-46163-2. Sci Rep. 2019. PMID: 31289316 Free PMC article.

2

Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells.

Almeida LC, Bauermeister A, Rezende-Teixeira P, Santos EAD, Moraes LAB, Machado-Neto JA, Costa-Lotufo LV. Almeida LC, et al. Biochem Pharmacol. 2019 Oct;168:38-47. doi: 10.1016/j.bcp.2019.06.016. Epub 2019 Jun 19. Biochem Pharmacol. 2019. PMID: 31228463

3

Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemia.

Carlos JAEG, Lima K, Coelho-Silva JL, de Melo Alves-Paiva R, Moreno NC, Vicari HP, de Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Carlos JAEG, et al. Cell Oncol (Dordr). 2020 Dec;43(6):1191-1201. doi: 10.1007/s13402-020-00551-3. Epub 2020 Aug 28. Cell Oncol (Dordr). 2020. PMID: 32857324

4

DNA damaging agents and DNA repair: From carcinogenesis to cancer therapy.

de Almeida LC, Calil FA, Machado-Neto JA, Costa-Lotufo LV. de Almeida LC, et al. Cancer Genet. 2021 Apr;252-253:6-24. doi: 10.1016/j.cancergen.2020.12.002. Epub 2020 Dec 9. Cancer Genet. 2021. PMID: 33340831 Review.

5

Synthetic cyclopenta[b]indoles exhibit antineoplastic activity by targeting microtubule dynamics in acute myeloid leukemia cells.

Vicari HP, Lima K, Gomes RDC, Fernandes DC, da Silva JCL, Rodrigues Junior MT, Barroso de Oliveira AS, Dos Santos RN, Andricopulo AD, Coelho F, Costa-Lotufo LV, Machado-Neto JA. Vicari HP, et al. Eur J Pharmacol. 2021 Mar 5;894:173853. doi: 10.1016/j.ejphar.2021.173853. Epub 2021 Jan 8. Eur J Pharmacol. 2021. PMID: 33422507

6

AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis.

Carlos JAEG, Lima K, Costa-Lotufo LV, Leitão A, Machado-Neto JA. Carlos JAEG, et al. Invest New Drugs. 2021 Aug;39(4):1139-1149. doi: 10.1007/s10637-021-01066-w. Epub 2021 Jan 21. Invest New Drugs. 2021. PMID: 33475938

7

Targeting glioma cells by antineoplastic activity of reversine.

Hirakata C, Lima K, De Almeida BO, De Miranda LBL, Florêncio KGD, Furtado LC, Costa-Lotufo LV, Machado-Neto JA. Hirakata C, et al. Oncol Lett. 2021 Aug;22(2):610. doi: 10.3892/ol.2021.12871. Epub 2021 Jun 15. Oncol Lett. 2021. PMID: 34188712 Free PMC article.

8

Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia.

Lipreri da Silva JC, Coelho-Silva JL, Lima K, Vicari HP, Lazarini M, Costa-Lotufo LV, Traina F, Machado-Neto JA. Lipreri da Silva JC, et al. Cell Oncol (Dordr). 2021 Oct;44(5):1105-1117. doi: 10.1007/s13402-021-00621-0. Epub 2021 Jul 1. Cell Oncol (Dordr). 2021. PMID: 34196912

9

Embelin potentiates venetoclax-induced apoptosis in acute myeloid leukemia cells.

Reis-Silva CSM, Branco PC, Lima K, Silva FL, Moreno PRH, Guallar V, Costa-Lotufo LV, Machado-Neto JA. Reis-Silva CSM, et al. Toxicol In Vitro. 2021 Oct;76:105207. doi: 10.1016/j.tiv.2021.105207. Epub 2021 Jul 1. Toxicol In Vitro. 2021. PMID: 34216723 Free article.

10

STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells.

Vicari HP, Coelho-Silva JL, Pereira-Martins DA, Lucena-Araujo AR, Lima K, Lipreri da Silva JC, Scheucher PS, Koury LC, de Melo RA, Bittencourt R, Pagnano K, Nunes E, Fagundes EM, Kerbauy F, de Figueiredo-Pontes LL, Costa-Lotufo LV, Rego EM, Traina F, Machado-Neto JA. Vicari HP, et al. Invest New Drugs. 2022 Apr;40(2):438-452. doi: 10.1007/s10637-021-01197-0. Epub 2021 Nov 27. Invest New Drugs. 2022. PMID: 34837603

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