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The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.
Rosa TLSA, Mendes MA, Linhares NRC, Rodrigues TF, Dias AA, Leal-Calvo T, Gandini M, Ferreira H, Costa FDMR, Sales AM, Amadeu TP, Schmitz V, Pinheiro RO, Rodrigues LS, Moraes MO, Pessolani MCV. Rosa TLSA, et al. Among authors: costa fdmr. Front Med (Lausanne). 2022 Jun 6;9:899998. doi: 10.3389/fmed.2022.899998. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35733868 Free PMC article.
PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves.
Díaz Acosta CC, Dias AA, Rosa TLSA, Batista-Silva LR, Rosa PS, Toledo-Pinto TG, Costa FDMR, Lara FA, Rodrigues LS, Mattos KA, Sarno EN, Bozza PT, Guilhot C, de Berrêdo-Pinho M, Pessolani MCV. Díaz Acosta CC, et al. Among authors: costa fdmr. PLoS Pathog. 2018 Jul 6;14(7):e1007151. doi: 10.1371/journal.ppat.1007151. eCollection 2018 Jul. PLoS Pathog. 2018. PMID: 29979790 Free PMC article.
Whole blood transcriptomics reveals the enrichment of neutrophil activation pathways during erythema nodosum leprosum reaction.
Rosa TLSA, Leal-Calvo T, Tavares IF, Mendes MA, Dias AA, Piauy MHDS, Barboza MFDS, Kapuscinski M, Costa FDMR, Marques MAM, Belone AFF, Sales AM, Hacker MA, Moreira MBP, Belisle JT, Moraes MO, Pessolani MCV, Schmitz V. Rosa TLSA, et al. Among authors: costa fdmr. Front Immunol. 2024 Apr 23;15:1366125. doi: 10.3389/fimmu.2024.1366125. eCollection 2024. Front Immunol. 2024. PMID: 38715615 Free PMC article.