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Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.
Gaspar L, Coron RP, KongThoo Lin P, Costa DM, Perez-Cabezas B, Tavares J, Roura-Ferrer M, Ramos I, Ronin C, Major LL, Ciesielski F, Pemberton IK, MacDougall J, Ciapetti P, Smith TK, Cordeiro-da-Silva A. Gaspar L, et al. Among authors: costa dm. PLoS Negl Trop Dis. 2018 Jan 22;12(1):e0006180. doi: 10.1371/journal.pntd.0006180. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29357372 Free PMC article.
Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei.
Graça NA, Gaspar L, Costa DM, Loureiro I, Thoo-Lin PK, Ramos I, Roura M, Pruvost A, Pemberton IK, Loukil H, MacDougall J, Tavares J, Cordeiro-da-Silva A. Graça NA, et al. Among authors: costa dm. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2532-6. doi: 10.1128/AAC.02490-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26787703 Free PMC article.
In vivo imaging of pathogen homing to the host tissues.
Tavares J, Costa DM, Teixeira AR, Cordeiro-da-Silva A, Amino R. Tavares J, et al. Among authors: costa dm. Methods. 2017 Aug 15;127:37-44. doi: 10.1016/j.ymeth.2017.05.008. Epub 2017 May 15. Methods. 2017. PMID: 28522323 Free article.
A role for hepcidin in the anemia caused by Trypanosoma brucei infection.
Neves JV, Gomes AC, Costa DM, Barroso C, Vaulont S, Cordeiro da Silva A, Tavares J, Rodrigues PNS. Neves JV, et al. Among authors: costa dm. Haematologica. 2021 Mar 1;106(3):806-818. doi: 10.3324/haematol.2019.227728. Haematologica. 2021. PMID: 31919087 Free PMC article.
MAEBL Contributes to Plasmodium Sporozoite Adhesiveness.
Sá M, Costa DM, Teixeira AR, Pérez-Cabezas B, Formaglio P, Golba S, Sefiane-Djemaoune H, Amino R, Tavares J. Sá M, et al. Among authors: costa dm. Int J Mol Sci. 2022 May 20;23(10):5711. doi: 10.3390/ijms23105711. Int J Mol Sci. 2022. PMID: 35628522 Free PMC article.
Immunization with CSP and a RIG-I Agonist is Effective in Inducing a Functional and Protective Humoral Response Against Plasmodium.
Teixeira AR, Pérez-Cabezas B, Costa DM, Sá M, Golba S, Sefiane-Djemaoune H, Ribeiro J, Kaneko I, Iwanaga S, Yuda M, Tsuji M, Boscardin SB, Amino R, Cordeiro-da-Silva A, Tavares J. Teixeira AR, et al. Among authors: costa dm. Front Immunol. 2022 May 20;13:868305. doi: 10.3389/fimmu.2022.868305. eCollection 2022. Front Immunol. 2022. PMID: 35669785 Free PMC article.
TRSP is dispensable for the Plasmodium pre-erythrocytic phase.
Costa DM, Sá M, Teixeira AR, Loureiro I, Thouvenot C, Golba S, Amino R, Tavares J. Costa DM, et al. Sci Rep. 2018 Oct 10;8(1):15101. doi: 10.1038/s41598-018-33398-8. Sci Rep. 2018. PMID: 30305687 Free PMC article.
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
Linciano P, Dawson A, Pöhner I, Costa DM, Sá MS, Cordeiro-da-Silva A, Luciani R, Gul S, Witt G, Ellinger B, Kuzikov M, Gribbon P, Reinshagen J, Wolf M, Behrens B, Hannaert V, Michels PAM, Nerini E, Pozzi C, di Pisa F, Landi G, Santarem N, Ferrari S, Saxena P, Lazzari S, Cannazza G, Freitas-Junior LH, Moraes CB, Pascoalino BS, Alcântara LM, Bertolacini CP, Fontana V, Wittig U, Müller W, Wade RC, Hunter WN, Mangani S, Costantino L, Costi MP. Linciano P, et al. Among authors: costa dm. ACS Omega. 2017 Sep 30;2(9):5666-5683. doi: 10.1021/acsomega.7b00473. Epub 2017 Sep 11. ACS Omega. 2017. PMID: 28983525 Free PMC article.
112 results