Costa ASH - Search Results

1

ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth.

Ma WK, Voss DM, Scharner J, Costa ASH, Lin KT, Jeon HY, Wilkinson JE, Jackson M, Rigo F, Bennett CF, Krainer AR. Ma WK, et al. Among authors: costa ash. Cancer Res. 2022 Mar 1;82(5):900-915. doi: 10.1158/0008-5472.CAN-20-0948. Cancer Res. 2022. PMID: 34921016 Free PMC article.

2

SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia.

Wei Y, Huang YH, Skopelitis DS, Iyer SV, Costa ASH, Yang Z, Kramer M, Adelman ER, Klingbeil O, Demerdash OE, Polyanskaya SA, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Vakoc CR. Wei Y, et al. Among authors: costa ash. Cancer Discov. 2022 Feb;12(2):450-467. doi: 10.1158/2159-8290.CD-20-1849. Epub 2021 Sep 16. Cancer Discov. 2022. PMID: 34531253 Free PMC article.

3

The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.

Xu R, Jones W, Wilcz-Villega E, Costa AS, Rajeeve V, Bentham RB, Bryson K, Nagano A, Yaman B, Olendo Barasa S, Wang Y, Chelala C, Cutillas P, Szabadkai G, Frezza C, Bianchi K. Xu R, et al. EMBO Rep. 2020 Sep 3;21(9):e48260. doi: 10.15252/embr.201948260. Epub 2020 Aug 11. EMBO Rep. 2020. PMID: 32783398 Free PMC article.

4

Metabolic Reprogramming and Oncogenesis: One Hallmark, Many Organelles.

Costa ASH, Frezza C. Costa ASH, et al. Int Rev Cell Mol Biol. 2017;332:213-231. doi: 10.1016/bs.ircmb.2017.01.001. Epub 2017 Mar 15. Int Rev Cell Mol Biol. 2017. PMID: 28526133 Review.

5

Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells.

Gonçalves E, Sciacovelli M, Costa ASH, Tran MGB, Johnson TI, Machado D, Frezza C, Saez-Rodriguez J. Gonçalves E, et al. Among authors: costa ash. Metab Eng. 2018 Jan;45:149-157. doi: 10.1016/j.ymben.2017.11.011. Epub 2017 Nov 27. Metab Eng. 2018. PMID: 29191787 Free PMC article.

6

Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.

Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Clerici S, et al. EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00071-9. Online ahead of print. EMBO Mol Med. 2024. PMID: 38684863 Free article.

7

Control of endothelial quiescence by FOXO-regulated metabolites.

Andrade J, Shi C, Costa ASH, Choi J, Kim J, Doddaballapur A, Sugino T, Ong YT, Castro M, Zimmermann B, Kaulich M, Guenther S, Wilhelm K, Kubota Y, Braun T, Koh GY, Grosso AR, Frezza C, Potente M. Andrade J, et al. Among authors: costa ash. Nat Cell Biol. 2021 Apr;23(4):413-423. doi: 10.1038/s41556-021-00637-6. Epub 2021 Apr 1. Nat Cell Biol. 2021. PMID: 33795871 Free PMC article.

8

CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism.

Thomas LW, Esposito C, Stephen JM, Costa ASH, Frezza C, Blacker TS, Szabadkai G, Ashcroft M. Thomas LW, et al. Among authors: costa ash. Cancer Metab. 2019 Jul 16;7:7. doi: 10.1186/s40170-019-0200-4. eCollection 2019. Cancer Metab. 2019. PMID: 31346464 Free PMC article.

9

Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis.

Bodineau C, Tomé M, Courtois S, Costa ASH, Sciacovelli M, Rousseau B, Richard E, Vacher P, Parejo-Pérez C, Bessede E, Varon C, Soubeyran P, Frezza C, Murdoch PDS, Villar VH, Durán RV. Bodineau C, et al. Among authors: costa ash. Nat Commun. 2021 Aug 10;12(1):4814. doi: 10.1038/s41467-021-25079-4. Nat Commun. 2021. PMID: 34376668 Free PMC article.

10

Author Correction: Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis.

O'Neill JS, Hoyle NP, Robertson JB, Edgar RS, Beale AD, Peak-Chew SY, Day J, Costa ASH, Frezza C, Causton HC. O'Neill JS, et al. Among authors: costa ash. Nat Commun. 2021 Dec 8;12(1):7269. doi: 10.1038/s41467-021-27497-w. Nat Commun. 2021. PMID: 34880246 Free PMC article. No abstract available.

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