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Transcriptional dynamics of induced pluripotent stem cell differentiation into β cells reveals full endodermal commitment and homology with human islets.
Pellegrini S, Chimienti R, Scotti GM, Giannese F, Lazarevic D, Manenti F, Poggi G, Lombardo MT, Cospito A, Nano R, Piemonti L, Sordi V. Pellegrini S, et al. Among authors: cospito a. Cytotherapy. 2021 Apr;23(4):311-319. doi: 10.1016/j.jcyt.2020.10.004. Epub 2020 Nov 24. Cytotherapy. 2021. PMID: 33246884 Free article.
Striatin knock out induces a gain of function of INa and impaired Ca2+ handling in mESC-derived cardiomyocytes.
Benzoni P, Arici M, Giannetti F, Cospito A, Prevostini R, Volani C, Fassina L, Rosato-Siri MD, Metallo A, Gennaccaro L, Suffredini S, Foco L, Mazzetti S, Calogero A, Cappelletti G, Leibbrandt A, Elling U, Broso F, Penninger JM, Pramstaller PP, Piubelli C, Bucchi A, Baruscotti M, Rossini A, Rocchetti M, Barbuti A. Benzoni P, et al. Among authors: cospito a. Acta Physiol (Oxf). 2024 May 15:e14160. doi: 10.1111/apha.14160. Online ahead of print. Acta Physiol (Oxf). 2024. PMID: 38747650
PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes.
Benzoni P, Da Dalt L, Elia N, Popolizio V, Cospito A, Giannetti F, Dell'Era P, Olesen MS, Bucchi A, Baruscotti M, Norata GD, Barbuti A. Benzoni P, et al. Among authors: cospito a. Front Physiol. 2023 Nov 13;14:1250951. doi: 10.3389/fphys.2023.1250951. eCollection 2023. Front Physiol. 2023. PMID: 38028792 Free PMC article.