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Synthesis and evaluation of analogs of 5'-(((Z)-4-amino-2-butenyl)methylamino)-5'-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity.
Brockway AJ, Volkov OA, Cosner CC, MacMillan KS, Wring SA, Richardson TE, Peel M, Phillips MA, De Brabander JK. Brockway AJ, et al. Among authors: cosner cc. Bioorg Med Chem. 2017 Oct 15;25(20):5433-5440. doi: 10.1016/j.bmc.2017.07.063. Epub 2017 Aug 3. Bioorg Med Chem. 2017. PMID: 28807574 Free PMC article.
Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).
Merkler DJ, Asser AS, Baumgart LE, Carballo N, Carpenter SE, Chew GH, Cosner CC, Dusi J, Galloway LC, Lowe AB, Lowe EW Jr, King L 3rd, Kendig RD, Kline PC, Malka R, Merkler KA, McIntyre NR, Romero M, Wilcox BJ, Owen TC. Merkler DJ, et al. Among authors: cosner cc. Bioorg Med Chem. 2008 Dec 1;16(23):10061-74. doi: 10.1016/j.bmc.2008.10.013. Epub 2008 Oct 11. Bioorg Med Chem. 2008. PMID: 18952446 Free PMC article.
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