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DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model.
Paluri SL, Burak M, Senejani AG, Levinson M, Rahim T, Clairmont K, Kashgarian M, Alvarado-Cruz I, Meas R, Cardó-Vila M, Zeiss C, Maher S, Bothwell ALM, Coskun E, Kant M, Jaruga P, Dizdaroglu M, Stephen Lloyd R, Sweasy JB. Paluri SL, et al. Among authors: coskun e. DNA Repair (Amst). 2021 Sep;105:103152. doi: 10.1016/j.dnarep.2021.103152. Epub 2021 Jun 24. DNA Repair (Amst). 2021. PMID: 34186496 Free PMC article.
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1.
Minko IG, Vartanian VL, Tozaki NN, Coskun E, Coskun SH, Jaruga P, Yeo J, David SS, Stone MP, Egli M, Dizdaroglu M, McCullough AK, Lloyd RS. Minko IG, et al. Among authors: coskun sh, coskun e. DNA Repair (Amst). 2020 Jan;85:102741. doi: 10.1016/j.dnarep.2019.102741. Epub 2019 Nov 2. DNA Repair (Amst). 2020. PMID: 31733589 Free PMC article.
Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).
Donley N, Jaruga P, Coskun E, Dizdaroglu M, McCullough AK, Lloyd RS. Donley N, et al. Among authors: coskun e. ACS Chem Biol. 2015 Oct 16;10(10):2334-43. doi: 10.1021/acschembio.5b00452. Epub 2015 Aug 7. ACS Chem Biol. 2015. PMID: 26218629 Free PMC article.
Characterization of rare NEIL1 variants found in East Asian populations.
Minko IG, Vartanian VL, Tozaki NN, Linde OK, Jaruga P, Coskun SH, Coskun E, Qu C, He H, Xu C, Chen T, Song Q, Jiao Y, Stone MP, Egli M, Dizdaroglu M, McCullough AK, Lloyd RS. Minko IG, et al. Among authors: coskun sh, coskun e. DNA Repair (Amst). 2019 Jul;79:32-39. doi: 10.1016/j.dnarep.2019.05.001. Epub 2019 May 3. DNA Repair (Amst). 2019. PMID: 31100703 Free PMC article.
Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity.
Marsden CG, Jaruga P, Coskun E, Maher RL, Pederson DS, Dizdaroglu M, Sweasy JB. Marsden CG, et al. Among authors: coskun e. Oncotarget. 2020 Jun 16;11(24):2262-2272. doi: 10.18632/oncotarget.27548. eCollection 2020 Jun 16. Oncotarget. 2020. PMID: 32595826 Free PMC article.
218 results