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Benzofuroxane derivatives as multi-effective agents for the treatment of cardiovascular diabetic complications. Synthesis, functional evaluation, and molecular modeling studies.
Sartini S, Cosconati S, Marinelli L, Barresi E, Di Maro S, Simorini F, Taliani S, Salerno S, Marini AM, Da Settimo F, Novellino E, La Motta C. Sartini S, et al. Among authors: cosconati s. J Med Chem. 2012 Dec 13;55(23):10523-31. doi: 10.1021/jm301124s. Epub 2012 Nov 20. J Med Chem. 2012. PMID: 23134227
tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.
Valente S, Trisciuoglio D, Tardugno M, Benedetti R, Labella D, Secci D, Mercurio C, Boggio R, Tomassi S, Di Maro S, Novellino E, Altucci L, Del Bufalo D, Mai A, Cosconati S. Valente S, et al. Among authors: cosconati s. ChemMedChem. 2013 May;8(5):800-11. doi: 10.1002/cmdc.201300005. Epub 2013 Mar 25. ChemMedChem. 2013. PMID: 23526814
Shading the TRF2 recruiting function: a new horizon in drug development.
Di Maro S, Zizza P, Salvati E, De Luca V, Capasso C, Fotticchia I, Pagano B, Marinelli L, Gilson E, Novellino E, Cosconati S, Biroccio A. Di Maro S, et al. Among authors: cosconati s. J Am Chem Soc. 2014 Dec 3;136(48):16708-11. doi: 10.1021/ja5080773. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25393214
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas.
Daniele S, La Pietra V, Barresi E, Di Maro S, Da Pozzo E, Robello M, La Motta C, Cosconati S, Taliani S, Marinelli L, Novellino E, Martini C, Da Settimo F. Daniele S, et al. Among authors: cosconati s. J Med Chem. 2016 May 26;59(10):4526-38. doi: 10.1021/acs.jmedchem.5b01767. Epub 2016 May 3. J Med Chem. 2016. PMID: 27050782
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer.
Morgillo F, Amendola G, Della Corte CM, Giacomelli C, Botta L, Di Maro S, Messere A, Ciaramella V, Taliani S, Marinelli L, Trincavelli ML, Martini C, Novellino E, Ciardiello F, Cosconati S. Morgillo F, et al. Among authors: cosconati s. J Med Chem. 2017 Sep 14;60(17):7447-7458. doi: 10.1021/acs.jmedchem.7b00794. Epub 2017 Aug 22. J Med Chem. 2017. PMID: 28787156
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors.
Salerno S, García-Argáez AN, Barresi E, Taliani S, Simorini F, La Motta C, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Via LD. Salerno S, et al. Among authors: cosconati s. Eur J Med Chem. 2018 Apr 25;150:446-456. doi: 10.1016/j.ejmech.2018.03.013. Epub 2018 Mar 7. Eur J Med Chem. 2018. PMID: 29547832
Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers.
Tomassi S, Ieranò C, Mercurio ME, Nigro E, Daniele A, Russo R, Chambery A, Baglivo I, Pedone PV, Rea G, Napolitano M, Scala S, Cosconati S, Marinelli L, Novellino E, Messere A, Di Maro S. Tomassi S, et al. Among authors: cosconati s. Bioorg Med Chem. 2018 May 15;26(9):2539-2550. doi: 10.1016/j.bmc.2018.04.017. Epub 2018 Apr 7. Bioorg Med Chem. 2018. PMID: 29656988
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
Ciaramella V, Della Corte CM, Di Mauro C, Tomassi S, Di Maro S, Troiani T, Martinelli E, Bianco R, Cosconati S, Pierantoni R, Meccariello R, Chianese R, Ciardiello F, Morgillo F. Ciaramella V, et al. Among authors: cosconati s. Oncotarget. 2018 Apr 10;9(27):19273-19282. doi: 10.18632/oncotarget.25018. eCollection 2018 Apr 10. Oncotarget. 2018. PMID: 29721201 Free PMC article.
127 results