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Page 1
Everolimus induces Met inactivation by disrupting the FKBP12/Met complex.
Raimondo L, D'Amato V, Servetto A, Rosa R, Marciano R, Formisano L, Di Mauro C, Orsini RC, Cascetta P, Ciciola P, De Maio AP, Di Renzo MF, Cosconati S, Bruno A, Randazzo A, Napolitano F, Montuori N, Veneziani BM, De Placido S, Bianco R. Raimondo L, et al. Among authors: cosconati s. Oncotarget. 2016 Jun 28;7(26):40073-40084. doi: 10.18632/oncotarget.9484. Oncotarget. 2016. PMID: 27223077 Free PMC article.
The G-triplex DNA.
Limongelli V, De Tito S, Cerofolini L, Fragai M, Pagano B, Trotta R, Cosconati S, Marinelli L, Novellino E, Bertini I, Randazzo A, Luchinat C, Parrinello M. Limongelli V, et al. Among authors: cosconati s. Angew Chem Int Ed Engl. 2013 Feb 18;52(8):2269-73. doi: 10.1002/anie.201206522. Epub 2013 Jan 17. Angew Chem Int Ed Engl. 2013. PMID: 23335456 No abstract available.
Src inhibitors act through different mechanisms in Non-Small Cell Lung Cancer models depending on EGFR and RAS mutational status.
Formisano L, D'Amato V, Servetto A, Brillante S, Raimondo L, Di Mauro C, Marciano R, Orsini RC, Cosconati S, Randazzo A, Parsons SJ, Montuori N, Veneziani BM, De Placido S, Rosa R, Bianco R. Formisano L, et al. Among authors: cosconati s. Oncotarget. 2015 Sep 22;6(28):26090-103. doi: 10.18632/oncotarget.4636. Oncotarget. 2015. PMID: 26325669 Free PMC article.
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
Amato J, Pagano A, Cosconati S, Amendola G, Fotticchia I, Iaccarino N, Marinello J, De Magis A, Capranico G, Novellino E, Pagano B, Randazzo A. Amato J, et al. Among authors: cosconati s. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1271-1280. doi: 10.1016/j.bbagen.2016.11.008. Epub 2016 Nov 9. Biochim Biophys Acta Gen Subj. 2017. PMID: 27836755
Structure-activity relationship of the exopolysaccharide from a psychrophilic bacterium: A strategy for cryoprotection.
Casillo A, Parrilli E, Sannino F, Mitchell DE, Gibson MI, Marino G, Lanzetta R, Parrilli M, Cosconati S, Novellino E, Randazzo A, Tutino ML, Corsaro MM. Casillo A, et al. Among authors: cosconati s. Carbohydr Polym. 2017 Jan 20;156:364-371. doi: 10.1016/j.carbpol.2016.09.037. Epub 2016 Sep 14. Carbohydr Polym. 2017. PMID: 27842835 Free PMC article.
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D. Musumeci D, et al. Among authors: cosconati s. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1341-1352. doi: 10.1016/j.bbagen.2017.01.024. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130159
Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.
Salvati E, Botta L, Amato J, Di Leva FS, Zizza P, Gioiello A, Pagano B, Graziani G, Tarsounas M, Randazzo A, Novellino E, Biroccio A, Cosconati S. Salvati E, et al. Among authors: cosconati s. J Med Chem. 2017 May 11;60(9):3626-3635. doi: 10.1021/acs.jmedchem.6b01563. Epub 2017 May 1. J Med Chem. 2017. PMID: 28445046
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
Ciaramella V, Della Corte CM, Di Mauro C, Tomassi S, Di Maro S, Troiani T, Martinelli E, Bianco R, Cosconati S, Pierantoni R, Meccariello R, Chianese R, Ciardiello F, Morgillo F. Ciaramella V, et al. Among authors: cosconati s. Oncotarget. 2018 Apr 10;9(27):19273-19282. doi: 10.18632/oncotarget.25018. eCollection 2018 Apr 10. Oncotarget. 2018. PMID: 29721201 Free PMC article.
Tailoring a lead-like compound targeting multiple G-quadruplex structures.
Amato J, Platella C, Iachettini S, Zizza P, Musumeci D, Cosconati S, Pagano A, Novellino E, Biroccio A, Randazzo A, Pagano B, Montesarchio D. Amato J, et al. Among authors: cosconati s. Eur J Med Chem. 2019 Feb 1;163:295-306. doi: 10.1016/j.ejmech.2018.11.058. Epub 2018 Nov 27. Eur J Med Chem. 2019. PMID: 30529547
128 results